ArticleClinical and translational allergy2023
Symptom control and health-related quality of life in allergic rhinitis with and without comorbid asthma: A multicentre European study.
Article in Clinical and translational allergy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Ginger-based formulations for allergic rhinitis disease: a systematic review and meta-analysis of experimental studies in animals and humans.Pharmaceutical biology · 2026Pooled it
- Exploring the Impact of Delivering Allergy Medication as Self-Care on Healthcare Greenhouse Gas Emissions in the United Kingdom.Advances in therapy · 2026Article
- Allergen extract-based sensitization patterns in mono-sensitized versus multi-sensitized patients with allergic rhinitis in Ningxia, China.Frontiers in allergy · 2026Article
- Factors Affecting Usage of a Digital Asthma Monitoring Application by Old-Age Asthmatics Living in Inner Central Portugal.Clinical interventions in aging · 2024Observational
- New progress in pediatric allergic rhinitis.Frontiers in immunology · 2024Review
- Allergic rhinitis: Review of the diagnosis and management: South African Allergic Rhinitis Working Group.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2023Review
- Obesity and Selected Allergic and Immunological Diseases-Etiopathogenesis, Course and Management.Nutrients · 2023Review
- Symptom control and health-related quality of life in allergic rhinitis with and without comorbid asthma: A multicentre European study.Clinical and translational allergy · 2023Article
Corrections and comments
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Authors and funding
23 authors at 8 institutions in 5 countries.
Funding
Abstract
backgroundAllergic rhinitis (AR) is a major non-communicable disease that affects the health-related quality of life (HRQoL) of patients. However, data on HRQoL and symptom control in AR patients with comorbid asthma (AR + asthma) are lacking.
methodsIn this multicentre, cross-sectional study, patients with AR were screened and administered questionnaires of demographic characteristics and health conditions (symptoms/diagnosis of AR and asthma, disease severity level, and allergic conditions). HRQoL was assessed using a modified version of the RHINASTHMA questionnaire (30, 'not at all bothered' - 150 'very much bothered') and symptom control was evaluated by a modified version of the Control of Allergic Rhinitis/Asthma Test (CARAT) (0, 'no control' - 30, 'very high control').
resultsOut of 643 patients with AR, 500 (78%) had asthma as a comorbidity, and 54% had moderate-severe intermittent AR, followed by moderate-severe persistent AR (34%). Compared to the patients with AR alone, patients with AR + asthma had significantly higher RHINASTHMA (e.g., median RHINASTHMA-total score 48.5 vs. 84, respectively) and a significantly lower CARAT score (median CARAT-total score 23 vs. 16.5, respectively). Upon stratifying asthma based on severity, AR patients with severe persistent asthma had worse HRQoL and control than those with mild persistent asthma. The association was significantly higher among non-obese participants compared to obese ones, with RHINASTHMA-upper symptoms score but not with CARAT.
conclusionsOur observation of poorer HRQoL and symptoms control in AR patients with comorbid asthma supports the importance of a comprehensive approach for the management of AR in case of a comorbid allergic condition.
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