Evidence map›Paper›PMID 36825227›Full record

ArticleFrontiers in veterinary science2023

Identification and analysis of differentially expressed (DE) circRNA in epididymis of yak and cattleyak.

Chunhai Li, Yan Yan, Cheng Pan, Michael Adjei, Khuram Shahzad, Peng Wang, Meilan Pan, Kerui Li, Ye Wang, Wangsheng Zhao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Epididymal-Born circRNA Cargo and Its Implications in Male Fertility.International journal of molecular sciences · 2025
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Chunhai LiSchool of Life Science and Engineering, Southwest University of Science and Technology, Mianyang, Sichuan, China.
Yan YanCollege of Life Sciences, Yan'an University, Yan'An, Shaanxi, China.
Cheng PanSchool of Life Science and Engineering, Southwest University of Science and Technology, Mianyang, Sichuan, China.
Michael AdjeiSchool of Life Science and Engineering, Southwest University of Science and Technology, Mianyang, Sichuan, China.
Khuram ShahzadDepartment of Biosciences, COMSATS University Islamabad, Islamabad, Pakistan.
Peng WangSchool of Life Science and Engineering, Southwest University of Science and Technology, Mianyang, Sichuan, China.
Meilan PanSchool of Life Science and Engineering, Southwest University of Science and Technology, Mianyang, Sichuan, China.
Kerui LiSchool of Life Science and Engineering, Southwest University of Science and Technology, Mianyang, Sichuan, China.
Ye WangSichuan Key Laboratory of Conservation Biology on Endangered Wildlife, Chengdu Research Base of Giant Panda Breeding, Chengdu, Sichuan, China.
Wangsheng ZhaoSchool of Life Science and Engineering, Southwest University of Science and Technology, Mianyang, Sichuan, China.
Southwest University of Science and Technology · CNChengdu Research Base of Giant Panda Breeding · CNCOMSATS University Islamabad · PKYan'an University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circular RNAs (circRNAs), as endogenous non-coding RNA with unique closed ring structure, is closely related to animal reproduction, and understanding the expression of circRNA in yak and cattleyak epididymal tissues is of great significance for understanding cattleyak sterility. Based on this, we screened and identified the differentially expressed circRNA in the epididymis of three yaks and two cattleyak. A total of 1,298 circRNAs were identified in the epididymis of yak and cattleyak, of which 137 differentially expressed (DE) circRNAs and the functions of some of them were elucidated in this research, as well as qPCR verification to 6 circRNAs from the 137 DE circRNAs. Gene Ontology (GO) enrichment analysis suggested that DE circRNAs were mainly related to metabolic process, development process, immune system process, reproductive process, reproduction, biological adhesion and growth. COG classification analysis showed that the DE circRNAs derived genes were mainly related to replication, recombination and repair. KEGG pathway analysis suggested that DE circRNAs were mainly involved in RNA degradation. In addition, we also screened Bta-mir-103, which is a circRNA binding miRNA related to sperm activity.

Indexed as

cattlecattleyakDE circRNAepididymistranscriptome sequencing

Identifiers

PMID36825227
PMCPMC9941329
OpenAlexW4319443947

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.