Evidence map›Paper›PMID 36825137›Full record

ArticleFrontiers in public health2023

Modeling COVID-19 infection dynamics and mitigation strategies for in-person K-6 instruction.

Douglas E Morrison, Roch Nianogo, Vladimir Manuel, Onyebuchi A Arah, Nathaniel Anderson, Tony Kuo, Moira Inkelas

Abstract read
In one paragraph

Article in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Douglas E MorrisonDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, Los Angeles, CA, United States.
Roch NianogoDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, Los Angeles, CA, United States.
Vladimir ManuelClinical and Translational Science Institute, University of California, Los Angeles, Los Angeles, CA, United States.
Onyebuchi A ArahDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, Los Angeles, CA, United States.
Nathaniel AndersonDepartment of Health Policy and Management, Fielding School of Public Health, University of California, Los Angeles, Los Angeles, CA, United States.
Tony KuoDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, Los Angeles, CA, United States.
Moira InkelasClinical and Translational Science Institute, University of California, Los Angeles, Los Angeles, CA, United States.

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
NRSA Training CoreTL1TR001883 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ALEX BUI, Nina Thawata Harawa · 2016 to 2026
$8.6M
Scientific and Technical CoreP2CHD041022 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Martha Jane Bailey · 2016 to 2026
$6.9M
Impact of COVID-19 testing and mitigation on equitable return-to-school in the second largest US school districtOT2HD108103 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI INKELAS, MOIRA, WONG, MITCHELL DAVID · 2021 to 2022
$3.0M
NCATS NIH HHS TL1 TR001883NCATS NIH HHS UL1 TR001881NICHD NIH HHS OT2 HD108103NICHD NIH HHS P2C HD041022
6 · The paper itself

Abstract

Background: U.S. school closures due to the coronavirus disease 2019 (COVID-19) pandemic led to extended periods of remote learning and social and economic impact on families. Uncertainty about virus dynamics made it difficult for school districts to develop mitigation plans that all stakeholders consider to be safe. Methods: We developed an agent-based model of infection dynamics and preventive mitigation designed as a conceptual tool to give school districts basic insights into their options, and to provide optimal flexibility and computational ease as COVID-19 science rapidly evolved early in the pandemic. Elements included distancing, health behaviors, surveillance and symptomatic testing, daily symptom and exposure screening, quarantine policies, and vaccination. Model elements were designed to be updated as the pandemic and scientific knowledge evolve. An online interface enables school districts and their implementation partners to explore the effects of interventions on outcomes of interest to states and localities, under a variety of plausible epidemiological and policy assumptions. Results: The model shows infection dynamics that school districts should consider. For example, under default assumptions, secondary infection rates and school attendance are substantially affected by surveillance testing protocols, vaccination rates, class sizes, and effectiveness of safety education. Conclusions: Our model helps policymakers consider how mitigation options and the dynamics of school infection risks affect outcomes of interest. The model was designed in a period of considerable uncertainty and rapidly evolving science. It had practical use early in the pandemic to surface dynamics for school districts and to enable manipulation of parameters as well as rapid update in response to changes in epidemiological conditions and scientific information about COVID-19 transmission dynamics, testing and vaccination resources, and reliability of mitigation strategies.

Indexed as

COVID-19HumansQuarantineReproducibility of ResultsSARS-CoV-2Schoolsagent-based modelCOVID-19K-6school districtsecondary transmission

Identifiers

PMID36825137
PMCPMC9941563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.