Evidence map›Paper›PMID 36825099›Full record

ArticleCase reports in oncology

Dosimetric Evaluation of the Uterus in Patients Receiving Total Body Irradiation with Ovarian Shielding.

Keiko Akahane, Shinichi Kako, Masato Suzuki, Yuta Takahashi, Shogo Hatanaka, Masahiro Kawahara, Yukari Nakada, Kazunari Ogawa, Satoru Takahashi, Yukiko Fukuda and 4 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Keiko AkahaneaDepartment of Radiology, Jichi Medical University Saitama Medical Center, Saitama, Japan.
Shinichi KakobDivision of Hematology, Jichi Medical University Saitama Medical Center, Saitama, Japan.
Masato SuzukiaDepartment of Radiology, Jichi Medical University Saitama Medical Center, Saitama, Japan.
Yuta TakahashiaDepartment of Radiology, Jichi Medical University Saitama Medical Center, Saitama, Japan.
Shogo HatanakacDepartment of Radiation Oncology, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
Masahiro KawaharaaDepartment of Radiology, Jichi Medical University Saitama Medical Center, Saitama, Japan.
Yukari NakadaaDepartment of Radiology, Jichi Medical University Saitama Medical Center, Saitama, Japan.
Kazunari OgawadDepartment of Radiology, Jichi Medical University, Tochigi, Japan.
Satoru TakahashidDepartment of Radiology, Jichi Medical University, Tochigi, Japan.
Yukiko FukudadDepartment of Radiology, Jichi Medical University, Tochigi, Japan.
Masashi EndodDepartment of Radiology, Jichi Medical University, Tochigi, Japan.
Noriko Oyama-ManabeaDepartment of Radiology, Jichi Medical University Saitama Medical Center, Saitama, Japan.
Yoshinobu KandabDivision of Hematology, Jichi Medical University Saitama Medical Center, Saitama, Japan.
Katsuyuki ShiraiaDepartment of Radiology, Jichi Medical University Saitama Medical Center, Saitama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infertility is a well-known late complication in patients receiving hematopoietic stem cell transplantation (HSCT). We previously reported that total body irradiation (TBI) with ovarian shielding reduces the radiation dose to the ovaries to 2.4 Gy - one-fifth of the dose compared to conventional TBI - and preserves fertility without increasing the risk of relapse. Exposure to the uterus and ovaries can reportedly affect pregnancy and childbirth. However, the dose constraint of the uterus that causes infertility remains unknown. Herein, we report the pregnancy and birth outcomes of 2 patients who gave birth following TBI with ovarian shielding and evaluated the dose to the uterus using a dose-volume histogram. Case 1 involved a 30-year-old woman with acute myeloid leukemia who underwent HSCT at 21 years of age with a uterus mean dose (

Indexed as

FertilityOvarian shieldingRadiation doseTotal body irradiationUterus

Identifiers

PMID36825099
PMCPMC9941773

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.