Evidence map›Paper›PMID 36825068›Full record

ArticleBiometrika2021

Hypotheses on a tree: new error rates and testing strategies.

Marina Bogomolov, Christine B Peterson, Yoav Benjamini, Chiara Sabatti

Abstract read
In one paragraph

Article in Biometrika, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Meta-analysis ofFrontiers in cellular and infection microbiology · 2025
    Pooled it
  2. Review
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  5. Associations of brain structure with psychopathy.European archives of psychiatry and clinical neuroscience · 2026
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  12. Short-term exposure to filter-bubble recommendation systems has limited polarization effects: Naturalistic experiments on YouTube.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  13. Article
  14. Controlling the False Split Rate in Tree-Based Aggregation.Journal of the American Statistical Association · 2025
    Article
  15. Review
  16. Article
  17. Combining Partial True Discovery Guarantee Procedures.Biometrical journal. Biometrische Zeitschrift · 2024
    Article
  18. Analysis of Microbiome Data.Annual review of statistics and its application · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marina BogomolovThe William Davidson Faculty of Industrial Engineering and Management, Technion-Israel Institute of Technology, Technion City, Haifa 3200003, Israel.
Christine B PetersonDepartment of Biostatistics, Division of Basic Science Research, The University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, U.S.A.
Yoav BenjaminiDepartment of Statistics and Operations Research, Tel-Aviv University, P.O. Box 39040, Tel-Aviv 6997801, Israel.
Chiara SabattiDepartment of Statistics, Stanford University, 50 Governor's Lane, Stanford, California 94305, U.S.A.

Funding

Genetic Regulation of Gene Expression and its Impact on Phenotypes - SupplementR01MH101782 · NIMH · STANFORD UNIVERSITY · PI SABATTI, CHIARA · 2013 to 2016
$1.3M
NIMH NIH HHS R01 MH101782
6 · The paper itself

Abstract

We introduce a multiple testing procedure that controls global error rates at multiple levels of resolution. Conceptually, we frame this problem as the selection of hypotheses that are organized hierarchically in a tree structure. We describe a fast algorithm and prove that it controls relevant error rates given certain assumptions on the dependence between the

Indexed as

False discovery rateHierarchical testingMultiple testingSelective inference

Identifiers

PMID36825068
PMCPMC9945647

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.