Evidence map›Paper›PMID 36825031›Full record

ArticleClinical kidney journal2022

Flank pain has a significant adverse impact on quality of life in ADPKD: the CYSTic-QoL study.

Jean Winterbottom, Roslyn J Simms, Anna Caroli, Emilie Cornec-Le Gall, Nathalie Demoulin, Monica Furlano, Esther Meijer, Olivier Devuyst, Ron T Gansevoort, Yannick Le-Meur and 3 more

Open access · goldAbstract read
In one paragraph

Article in Clinical kidney journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  4. Review
  5. Article
  6. Foam sclerotherapy for symptomatic cysts in ADPKD, ADPLD and solitary cysts.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Observational
  7. Review
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 6 countries.

Jean WinterbottomAcademic Nephrology Unit, Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK.
Roslyn J SimmsAcademic Nephrology Unit, Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK.
Anna CaroliIstituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.
Emilie Cornec-Le GallBrest University, Inserm, UMR 1078, GGB, CHU Brest, Brest, France.ORCID https://orcid.org/0000-0003-1958-4459
Nathalie DemoulinCliniques Universitaires Saint-Luc, Université Catholique de Louvain Medical School, Brussels, Belgium.ORCID https://orcid.org/0000-0002-3566-3950
Monica FurlanoInherited Kidney Disorders, Nephrology Department, Fundació Puigvert, IIB Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.
Esther MeijerDepartment of Nephrology, University Medical Centre Groningen, Groningen, The Netherlands.
Olivier DevuystCliniques Universitaires Saint-Luc, Université Catholique de Louvain Medical School, Brussels, Belgium.ORCID https://orcid.org/0000-0003-3744-4767
Ron T GansevoortDepartment of Nephrology, University Medical Centre Groningen, Groningen, The Netherlands.
Yannick Le-MeurBrest University, Inserm, UMR 1227, LBAI, CHU Brest, Brest, France.
Norberto PericoIstituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.
Roser TorraInherited Kidney Disorders, Nephrology Department, Fundació Puigvert, IIB Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.ORCID https://orcid.org/0000-0001-8714-2332
Albert C M OngAcademic Nephrology Unit, Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK.ORCID https://orcid.org/0000-0002-7211-5400
Sheffield Teaching Hospitals NHS Foundation Trust · GBCliniques Universitaires Saint-Luc · BEInserm · FRMario Negri Institute for Pharmacological Research · ITUniversitat Autònoma de Barcelona · ESUniversity Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disorder and a major cause of kidney failure worldwide. However, its impact on quality-of-life has not been systematically explored. Methods: The CYSTic-QoL study was an observational study designed to study quality-of-life in adult European ADPKD patients with an estimated glomerular filtration rate (eGFR) ≥30 mL/min/1.73 m Results: The mean age of participants was 43 years and 55% were female, with a mean eGFR of 77 mL/min/1.73 m Conclusion: ADPKD patients suffer from significantly decreased QoL in multiple domains, exacerbated particularly by chronic pain.

Indexed as

ADPKDkidney functionpainquality-of-lifetotal kidney volume

Identifiers

PMID36825031
PMCPMC9942441
OpenAlexW4283207312

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.