Evidence map›Paper›PMID 36824965›Full record

ArticlebioRxiv : the preprint server for biology2023

Human gene regulatory evolution is driven by the divergence of regulatory element function in both

Tyler Hansen, Sarah Fong, John A Capra, Emily Hodges

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Tyler HansenDepartment of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37212, USA.
Sarah FongVanderbilt Genetics Institute, Vanderbilt University School of Medicine, Nashville, TN 37212, USA.
John A CapraBakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA 94143, USA.
Emily HodgesDepartment of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37212, USA.
University of California, San Francisco · USVanderbilt University · US

Funding

The Evolution of Gene Regulation and Human DiseaseR35GM127087 · NIGMS · VANDERBILT UNIVERSITY · PI John Anthony Capra · 2018 to 2026
$3.2M
Training Program on Genetic Variation and Human PhenotypesT32GM080178 · NIGMS · VANDERBILT UNIVERSITY · PI COX, NANCY J, SAMUELS, DAVID C · 2007 to 2021
$3.1M
Decoding genome function with DNA methylation and human phenome dataR01GM147078 · NIGMS · VANDERBILT UNIVERSITY · PI Emily Hodges · 2022 to 2026
$1.9M
NIGMS NIH HHS R01 GM147078NIGMS NIH HHS R35 GM127087NIGMS NIH HHS T32 GM080178
6 · The paper itself

Abstract

Gene regulatory divergence between species can result from

Indexed as

Comparative GenomicsDNA Regulatory ElementsFunctional GenomicsGene RegulationHuman EvolutionLymphoblastoid Cell LinesMassively Parallel Reporter Assays

Identifiers

PMID36824965
PMCPMC9949080
OpenAlexW4320917732

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.