Evidence map›Paper›PMID 36824891›Full record

ArticleResearch square2023

Chronic wound microenvironment mediates selection of biofilm-forming multi drug resistant

Miroslav Dinic, Rebecca Verpile, Jingjing Meng, Jelena Marjanovic, Jamie L Burgess, Lisa Plano, Suzanne Hower, Seth R Thaller, Santanu Banerjee, Hadar Lev-Tov and 2 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 1 institution in 2 countries.

Miroslav DinicWound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Rebecca VerpileWound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Jingjing MengWound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Jelena MarjanovicWound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Jamie L BurgessWound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Lisa PlanoDepartment of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, USA.
Suzanne HowerDepartment of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, USA.
Seth R ThallerDepartment of Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Santanu BanerjeeDepartment of Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Hadar Lev-TovWound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Marjana Tomic-CanicWound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Irena PastarWound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID 0000-0003-0197-6198
University of Miami · US

Funding

Prevention of intracellular infection in diabetic wounds by commensal Staphylococcus epidermidisR01DK136241 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Irena Pastar, NATASA STRBO · 2023 to 2026
$2.8M
Developing strategies for effective debridement in patients for venous leg ulcersR01AR073614 · NIAMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI KIRSNER, ROBERT SCOTT, TOMIC-CANIC, MARJANA · 2018 to 2023
$2.6M
Core mechanisms that contribute to inhibition of wound healing in diabetic foot and venous leg ulcersF30DK132806 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Jamie Lee Burgess · 2022 to 2026
$245k
NIAMS NIH HHS R01 AR073614NIDDK NIH HHS F30 DK132806NIDDK NIH HHS R01 DK136241
6 · The paper itself

Abstract

Venous leg ulcers (VLU) are the most common chronic wounds characterized by bacterial biofilms and perturbed microbiome.

Indexed as

antimicrobial resistancebiofilmchronic woundsStaphylococcus epidermidiswound healing

Identifiers

PMID36824891
PMCPMC9949177
OpenAlexW4321219947

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.