Evidence map›Paper›PMID 36824888›Full record

ArticlebioRxiv : the preprint server for biology2023

Disease-causing Slack potassium channel mutations produce opposite effects on excitability of excitatory and inhibitory neurons.

Jing Wu, Imran H Quraishi, Yalan Zhang, Mark Bromwich, Leonard K Kaczmarek

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jing Wu
Imran H Quraishi
Yalan Zhang
Mark Bromwich
Leonard K Kaczmarek
Yale University · US

Funding

Cellular Regulation of Sodium-activated Potassium ChannelsR01NS102239 · NINDS · YALE UNIVERSITY · PI LEONARD K KACZMAREK · 2018 to 2026
$3.5M
NINDS NIH HHS R01 NS102239
6 · The paper itself

Abstract

In brief: In a genetic mouse model of Na Highlights: GOF mutations in Slack potassium channel cause elevated outward K

Identifiers

PMID36824888
PMCPMC9948954
OpenAlexW4320715902

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.