Evidence map›Paper›PMID 36824875›Full record

ArticlemedRxiv : the preprint server for health sciences2023

Psychometric Properties of the NIH Toolbox Cognition and Emotion Batteries Among Children and Adolescents with Congenital Heart Defects.

Julia Wallace, Rafael Ceschin, Vince K Lee, Nancy H Beluk, Cheryl Burns, Sue Beers, Cecilia Lo, Ashok Panigrahy, Daryaneh Badaly

Registry-linked trialOpen access · greenAbstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06326996 (Thiamine Intervention and Cognition in Older Adults Undergoing Coronary Artery Bypass Grafting - A Randomized Clinical Trial.), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06326996 early_phase1recruitingnot on this mapstarted 2024, after this paper: background citation

Thiamine Intervention and Cognition in Older Adults Undergoing Coronary Artery Bypass Grafting - A Randomized Clinical Trial.

TypeinterventionalSponsorUniversity of California, Los AngelesRan2024 to 2026Enrolled52ConditionsCoronary Heart Disease, Coronary Artery Bypass GraftingArmsThiamine, Placebo
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Julia WallaceDepartment of Radiology, University of Pittsburgh School of Medicine.
Rafael CeschinDepartment of Radiology, University of Pittsburgh School of Medicine.
Vince K LeeDepartment of Radiology, University of Pittsburgh School of Medicine.
Nancy H BelukDepartment of Radiology, University of Pittsburgh School of Medicine.
Cheryl BurnsDepartment of Psychiatry, University of Pittsburgh Medical Center.
Sue BeersDepartment of Psychiatry, University of Pittsburgh School of Medicine.
Cecilia LoDepartment of Developmental Biology, University of Pittsburgh School of Medicine.
Ashok PanigrahyDepartment of Radiology, University of Pittsburgh School of Medicine.
Daryaneh BadalyLearning and Development Center, Child Mind Institute.
University of Pittsburgh · USChild Mind Institute · USUniversity of Pittsburgh Medical Center · US

Funding

The internship in Biomedical Research, Informatics, and Computer Science (iBRIC): Biomedical Informatics and Data Science research experiences for students from Minority Serving InstitutionsT15LM007059 · NLM · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HARRY S HOCHHEISER · 1987 to 2026
$23.9M
SVRIII: Brain Connectome and Neurodevelopment OutcomesR01HL128818 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PANIGRAHY, ASHOK · 2015 to 2019
$3.5M
Modeling Cerebral Microbleeds and Striatal Brain Iron in Adult Congenital Heart Disease in Relationship to Differential Genetic Risk for Alzheimer DiseaseR01HL152740 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CESCHIN, RAFAEL C, GURVITZ, MICHELLE · 2020 to 2023
$2.2M
NHLBI NIH HHS R01 HL128818NHLBI NIH HHS R01 HL152740NLM NIH HHS T15 LM007059
6 · The paper itself

Abstract

Objective: The NIH Toolbox offers brief, computerized measures of cognitive and psychosocial functioning. However, its psychometric properties were established among typically developing children and adolescents. The current study provides the first comprehensive assessment of its psychometric properties among young patients with congenital heart defects (CHD). Study Design: We prospectively recruited 58 patients with CHD and 80 healthy controls between the ages of 6 and 17. Participants completed the NIH Toolbox Cognition and Emotion Batteries, a battery of clinician-administered neuropsychological tests, and ratings of their quality of life. Their parents also completed ratings of their functioning. Results: On the Cognition Battery, we found expectable group differences and developmentally expected gains across ages. For the most part, composites and subtests were significantly correlated with neuropsychological measures of similar constructs. Higher scores were generally associated with ratings of better day-to-day functioning among children with CHD. On the Emotion Battery, we found no significant group differences, echoing prior research. For the most part, scales showed acceptable internal consistency among both groups. There was adequate construct coherence for most of questionnaires among healthy control but not participants with CHD. Correlations with a comparison tool were largely within expectable directions. Conclusion: The NIH Toolbox may provide a valid and useful assessment of cognitive functioning among children and adolescents with CHD. While it may offer reliable and valid scales of psychosocial functioning, further research is needed to understand the meaningfulness of the scales for participants with CHD.

Identifiers

PMID36824875
PMCPMC9949204
OpenAlexW4320718784

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.