Evidence map›Paper›PMID 36824869›Full record

ArticleResearch square2024

HIV-1 interaction with an

Daniel W Heindel, Dania M Figueroa Acosta, Marisa Goff, Clauvis Kunkeng Yengo, Muzafar Jan, Xiaomei Liu, Xiao-Hong Wang, Mariya I Petrova, Mo Zhang, Manish Sagar and 9 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 3 countries.

Daniel W HeindelDivison of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Dania M Figueroa AcostaDivison of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Marisa GoffDivison of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Clauvis Kunkeng YengoDivison of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Muzafar JanDivison of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Xiaomei LiuDivison of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Xiao-Hong WangVA New York Harbor Healthcare System-Manhattan, New York, New York, United States of America.
Mariya I PetrovaDepartment of Bioscience Engineering, University of Antwerp, Antwerp, Belgium.
Mo ZhangDepartment of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.
Manish SagarDepartment of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.
Phillip BarnetteDivision of Pathobiology and Immunology, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA.
Shilpi PandeyDivision of Pathobiology and Immunology, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA.
Ann J HessellDivision of Pathobiology and Immunology, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA.
Kun-Wei ChanDepartment of Biochemistry and Molecular Pharmacology New York University Grossman School of Medicine, New York, NY, USA.ORCID 0000-0001-5384-6198
Xiang-Peng KongDepartment of Biochemistry and Molecular Pharmacology New York University Grossman School of Medicine, New York, NY, USA.
Benjamin K ChenDivison of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Lara K MahalDepartment of Chemistry, University of Alberta, Edmonton, Alberta, Canada.ORCID 0000-0003-4791-8524
Barbara A BensingDepartment of Medicine, San Francisco Veterans Affairs Medical Center and University of California, San Francisco, CA, USA.
Catarina E HioeDivison of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-9245-9788
Icahn School of Medicine at Mount Sinai · USNYU Langone Health · USUniversity of Alberta · CANew York University · USUniversity of Antwerp · BEVA NY Harbor Healthcare System · US

Funding

TRAINING PROGRAM: MECHANISMS OF VIRUS-HOST INTERACTIONST32AI007647 · NIAID · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI Domenico Tortorella · 2000 to 2026
$11.5M
Structure and immunogenicity of novel trimeric HIV-1 Env immunogensR01AI145655 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI KONG, XIANGPENG · 2019 to 2023
$4.7M
Using immune complex vaccines to optimize antibody responses to HIV EnvR01AI148327 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HIOE, CATARINA E · 2020 to 2025
$4.5M
Harnessing Abs specific for immunogenic and conserved Env epitopes to protect against HIVR01AI139290 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HIOE, CATARINA E · 2018 to 2022
$4.1M
HIV immune evasion and escape through T cell virological synapsesR37AI148064 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BENJAMIN K CHEN · 2022 to 2026
$3.1M
HIV immune evasion and escape through T cell virological synapsesR56AI148064 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CHEN, BENJAMIN K · 2020 to 2020
$538k
Biologic consequences of HIV-1 interaction with bacteriaR21AI150909 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HIOE, CATARINA E · 2020 to 2021
$501k
Using streptococcal sialoglycan binding proteins to characterize MUC7 glycoformsR03DE029516 · NIDCR · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI BENSING, BARBARA ANNE · 2020 to 2021
$307k
Effect of an Fc Gamma Receptor Polymorphism on Antibody-Dependent Enhancement of Zika Virus InfectionF31AI154695 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GOFF, MARISA · 2021 to 2023
$136k
BLR&D Research Career Scientist Award ApplicationIK6BX004607 · VA · JAMES J PETERS VA MEDICAL CENTER · PI HIOE, CATARINA E · 2019 to 2025
–
Understanding Th-monocyte interactions in HIV infectionI01BX003860 · VA · JAMES J PETERS VA MEDICAL CENTER · PI HIOE, CATARINA E · 2018 to 2021
–
BLRD VA I01 BX003860BLRD VA IK6 BX004607NIAID NIH HHS F31 AI154695NIAID NIH HHS R01 AI139290NIAID NIH HHS R01 AI145655NIAID NIH HHS R01 AI148327NIAID NIH HHS R21 AI150909NIAID NIH HHS R37 AI148064NIAID NIH HHS R56 AI148064NIAID NIH HHS T32 AI007647NIDCR NIH HHS R03 DE029516
6 · The paper itself

Abstract

Bacteria dysbiosis has been associated with an increased risk of HIV-1 transmission and acquisition. The prevalent idea is that bacteria dysbiosis compromises mucosal integrity and promotes inflammatory conditions to cause recruitment and activation of immune cells that harbor or are targeted by HIV-1. However, it is also possible that HIV-1 directly binds bacteria or bacterial products to impact virus infectivity and transmissibility. This study evaluated HIV-1 interactions with bacteria through glycan-binding lectins. The

Indexed as

bacteriaglycosylationHIVlectinO-glycan

Identifiers

PMID36824869
PMCPMC9949255
OpenAlexW4321184643

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.