Evidence map›Paper›PMID 36824802›Full record

ArticleResearch square2023

Ionic Liquid Coating-Driven Nanoparticle Delivery to the Brain: Applications for NeuroHIV.

Christine M Hamadani, Fakhri Mahdi, Anya Merrell, Jack Flanders, Ruofan Cao, Priyavrat Vashisth, Mercedes C Pride, Alysha N Hunter, Gagandeep Singh, Gregg Roman and 2 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Christine M HamadaniUniversity of Mississippi.
Fakhri MahdiUniversity of Mississippi.
Anya MerrellUniversity of Mississippi.
Jack FlandersUniversity of Mississippi.
Ruofan CaoUniversity of Mississippi.
Priyavrat VashisthUniversity of Mississippi.
Mercedes C PrideUniversity of Mississippi.
Alysha N HunterUniversity of Mississippi.
Gagandeep SinghUniversity of Mississippi.
Gregg RomanUniversity of Mississippi.
Jason J ParisUniversity of Mississippi.
Eden E L TannerUniversity of Mississippi.ORCID 0000-0002-7919-2249
University of Mississippi · US

Funding

Tracking Glycosylation State with Fluorinated Glycosides ProbesP20GM130460 · NIGMS · UNIVERSITY OF MISSISSIPPI · PI Joshua S Sharp · 2020 to 2026
$17.9M
Pilot Project ProgramP30GM122733 · NIGMS · UNIVERSITY OF MISSISSIPPI · PI WILLETT, KRISTINE L · 2018 to 2022
$5.3M
Ionic liquid-assisted drug delivery to brain reservoirs for treatment of neuroHIVR01DA056875 · NIDA · UNIVERSITY OF MISSISSIPPI · PI Jason Richard Paris, Eden Tanner · 2023 to 2026
$2.2M
Laser spectroscopic instrumentation for isotopic sensing of biogenic Nitric OxideR21GM103460 · NIGMS · PRINCETON UNIVERSITY · PI WYSOCKI, GERARD · 2012 to 2012
$190k
NIDA NIH HHS R01 DA056875NIGMS NIH HHS P20 GM130460NIGMS NIH HHS P30 GM122733NIGMS NIH HHS R21 GM103460
6 · The paper itself

Abstract

Delivering cargo to the central nervous system (CNS) remains a pharmacological challenge. For infectious diseases such as HIV, the CNS acts as a latent reservoir that is inadequately managed by systemic antiretrovirals (ARTs). ARTs thus cannot eradicate HIV, and given CNS infection, patients experience an array of neurological deficits that are collectively referred to as 'neuroHIV'. Herein we report the development of bioinspired ionic liquid-coated nanoparticles (IL-NPs) for

Identifiers

PMID36824802
PMCPMC9949257
OpenAlexW4320712742

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.