Evidence map›Paper›PMID 36824744›Full record

ArticlebioRxiv : the preprint server for biology2023

Single-strand mismatch and damage patterns revealed by single-molecule DNA sequencing.

Mei Hong Liu, Benjamin Costa, Una Choi, Rachel C Bandler, Emilie Lassen, Marta Grońska-Pęski, Adam Schwing, Zachary R Murphy, Daniel Rosenkjær, Shany Picciotto and 12 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 10 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors at 6 institutions in 2 countries.

Mei Hong LiuCenter for Human Genetics and Genomics, New York University Grossman School of Medicine, USA.
Benjamin CostaCenter for Human Genetics and Genomics, New York University Grossman School of Medicine, USA.
Una ChoiCenter for Human Genetics and Genomics, New York University Grossman School of Medicine, USA.
Rachel C BandlerCenter for Human Genetics and Genomics, New York University Grossman School of Medicine, USA.
Emilie LassenCryos International Sperm and Egg Bank, Denmark.
Marta Grońska-PęskiCenter for Human Genetics and Genomics, New York University Grossman School of Medicine, USA.
Adam SchwingCenter for Human Genetics and Genomics, New York University Grossman School of Medicine, USA.
Zachary R MurphyCenter for Human Genetics and Genomics, New York University Grossman School of Medicine, USA.
Daniel RosenkjærCryos International Sperm and Egg Bank, Denmark.
Shany PicciottoDepartment of Urology, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, USA.
Vanessa BianchiProgram in Genetics and Genome Biology, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Canada.
Lucie StengsProgram in Genetics and Genome Biology, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Canada.
Melissa EdwardsProgram in Genetics and Genome Biology, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Canada.
Caitlin A LohCenter for Human Genetics and Genomics, New York University Grossman School of Medicine, USA.
Tina K TruongCenter for Human Genetics and Genomics, New York University Grossman School of Medicine, USA.
Randall E BrandDepartment of Medicine, University of Pittsburgh School of Medicine, USA.
Tomi PastinenGenomic Medicine Center, Children's Mercy Kansas City, USA.
J Richard WagnerDepartment of Nuclear Medicine and Radiobiology, Université de Sherbrooke, Canada.
Anne-Bine SkytteCryos International Sperm and Egg Bank, Denmark.
Uri TaboriProgram in Genetics and Genome Biology, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Canada.
Jonathan E ShoagDepartment of Urology, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, USA.
Gilad D EvronyCenter for Human Genetics and Genomics, New York University Grossman School of Medicine, USA.
Center for Human Genetics · USHospital for Sick Children · CAUniversity School · USChildren's Mercy Hospital · USUniversité de Sherbrooke · CAUniversity of Pittsburgh · US

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Richard Lewis Possemato · 1985 to 2026
$83.1M
Postdoctoral Research Training in Neurodegenerative Disorders and the Aging BrainT32AG052909 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Helen E Scharfman, THOMAS M WISNIEWSKI · 2017 to 2026
$2.5M
Single-cell genomic approaches to study the cellular origins of brain tumorsDP5OD028158 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI EVRONY, GILAD DAVID · 2019 to 2023
$2.1M
Direct measurement of the male germline mutation rate using sequential sperm samplesR21HD105910 · NICHD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI EVRONY, GILAD DAVID, SHOAG, JONATHAN · 2021 to 2022
$479k
Measurement of cell-type specific somatic mutation rates in the aging human brain - Resubmission – 1F32AG076287 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI GRONSKA-PESKI, MARTA · 2022 to 2023
$139k
NCI NIH HHS P30 CA016087NIA NIH HHS F32 AG076287NIA NIH HHS T32 AG052909NICHD NIH HHS R21 HD105910NIH HHS DP5 OD028158
6 · The paper itself

Abstract

Mutations accumulate in the genome of every cell of the body throughout life, causing cancer and other genetic diseases

Identifiers

PMID36824744
PMCPMC9949150
OpenAlexW4321350133

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.