Evidence map›Paper›PMID 36824743›Full record

ArticlebioRxiv : the preprint server for biology2023

Direct long read visualization reveals metabolic interplay between two antimalarial drug targets.

Shiwei Liu, Emily R Ebel, Aleksander Luniewski, Julia Zulawinska, Mary Lewis Simpson, Jane Kim, Nnenna Ene, Thomas Werner Anthony Braukmann, Molly Congdon, Webster Santos and 2 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Shiwei LiuUniversity of Virginia, Department of Biology, Charlottesville, VA, USA.
Emily R EbelStanford, Departments of Pediatrics and Microbiology & Immunology, Stanford, CA, USA.ORCID 0000-0002-3244-4250
Aleksander LuniewskiUniversity of Virginia, Department of Biology, Charlottesville, VA, USA.
Julia ZulawinskaUniversity of Virginia, Department of Biology, Charlottesville, VA, USA.
Mary Lewis SimpsonUniversity of Virginia, Department of Biology, Charlottesville, VA, USA.
Jane KimUniversity of Virginia, Department of Biology, Charlottesville, VA, USA.
Nnenna EneUniversity of Virginia, Department of Biology, Charlottesville, VA, USA.
Thomas Werner Anthony BraukmannStanford University, Departments of Pathology and Microbiology & Immunology, Stanford, CA, USA.
Molly CongdonVirginia Tech, Department of Chemistry, Blacksburg, VA, USA.
Webster SantosVirginia Tech, Department of Chemistry, Blacksburg, VA, USA.
Ellen YehStanford University, Departments of Pathology and Microbiology & Immunology, Stanford, CA, USA.
Jennifer L GulerUniversity of Virginia, Department of Biology, Charlottesville, VA, USA.ORCID 0000-0001-6301-4563
University of Virginia · USStanford University · USVirginia Tech · US

Funding

The evolution of copy number variations in the AT-rich Plasmodium genomeR01AI150856 · NIAID · UNIVERSITY OF VIRGINIA · PI GULER, JENNIFER LYNN · 2021 to 2025
$2.0M
NIAID NIH HHS R01 AI150856
6 · The paper itself

Abstract

Increases in the copy number of large genomic regions, termed genome amplification, are an important adaptive strategy for malaria parasites. Numerous amplifications across the

Identifiers

PMID36824743
PMCPMC9948948
OpenAlexW4320489872

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.