Evidence map›Paper›PMID 36824690›Full record

ArticlePulmonary circulation2023

Metallomics in pulmonary arterial hypertension patients.

Karim El-Kersh, C Danielle Hopkins, Xiaoyong Wu, Shesh N Rai, Matthew C Cave, M Ryan Smith, Young-Mi Go, Dean P Jones, Lu Cai, Jiapeng Huang

Open access · goldAbstract read
In one paragraph

Article in Pulmonary circulation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Karim El-KershDivision of Pulmonary Critical Care and Sleep Medicine, Department of Internal Medicine University of Nebraska Medical Center Omaha Nebraska USA.ORCID 0000-0003-1285-3628
C Danielle HopkinsDepartment of Anesthesiology and Perioperative Medicine University of Louisville School of Medicine Louisville Kentucky USA.
Xiaoyong WuDepartment of Environmental Health University of Cincinnati Cincinnati Ohio USA.
Shesh N RaiDepartment of Environmental Health University of Cincinnati Cincinnati Ohio USA.
Matthew C CaveDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine University of Louisville School of Medicine Louisville Kentucky USA.
M Ryan SmithDivision of Pulmonary, Allergy and Critical Care Medicine Emory University Atlanta Georgia USA.
Young-Mi GoDivision of Pulmonary, Allergy and Critical Care Medicine Emory University Atlanta Georgia USA.
Dean P JonesDivision of Pulmonary, Allergy and Critical Care Medicine Emory University Atlanta Georgia USA.
Lu CaiThe Center for Integrative Environmental Health Sciences University of Louisville Louisville Kentucky USA.
Jiapeng HuangDepartment of Anesthesiology and Perioperative Medicine University of Louisville School of Medicine Louisville Kentucky USA.ORCID 0000-0002-4794-8400
University of Louisville · USEmory University · USCincinnati Health Department · USUniversity of Nebraska Medical Center · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Role of oxidized linoleic acid metabolites in the pathogenesis of alcoholic liver diseaseP20GM113226 · NIGMS · UNIVERSITY OF LOUISVILLE · PI GHARE, SMITA S · 2016 to 2025
$24.1M
Pilot Project ProgramP30ES019776 · NIEHS · EMORY UNIVERSITY · PI Carmen Joseph Marsit · 2013 to 2026
$22.6M
Superfund Training CoreP42ES023716 · NIEHS · UNIVERSITY OF LOUISVILLE · PI FORTNER, JOHN · 2017 to 2025
$18.1M
University of Louisville Center for Integrative Environmental Health SciencesP30ES030283 · NIEHS · UNIVERSITY OF LOUISVILLE · PI J CHRISTOPHER STATES · 2020 to 2026
$10.0M
Dissecting the pathogenesis and outcomes of PSC using multi-omics by studying the exposome and genomeRC2DK118619 · NIDDK · MAYO CLINIC ROCHESTER · PI LAZARIDIS, KONSTANTINOS N · 2018 to 2022
$7.8M
Environmental Liver DiseaseR35ES028373 · NIEHS · UNIVERSITY OF LOUISVILLE · PI CAVE, MATTHEW C · 2017 to 2024
$4.0M
Fibroblast Growth Factor 1 Prevents Hyperlipidemia and atherosclerosisR01HL160927 · NHLBI · UNIVERSITY OF LOUISVILLE · PI Yi Tan · 2022 to 2026
$2.7M
Cadmium-potentiated metabolic reprogramming in pathogenesis of lung fibrosisR01ES031980 · NIEHS · EMORY UNIVERSITY · PI GO KANG, YOUNG-MI · 2021 to 2025
$2.2M
A Handheld Microchip for GC analysis of breath to screen for COVID-19U18TR003787 · NCATS · UNIVERSITY OF LOUISVILLE · PI FU, XIAO-AN, NANTZ, MICHAEL H · 2021 to 2022
$2.0M
A novel mechanism of stromal cell-derived factor 1 protection against diabetic cardiomyopathyR01HL125877 · NHLBI · UNIVERSITY OF LOUISVILLE · PI TAN, YI · 2017 to 2021
$1.9M
Exposome and Precision Medicine in NAFLDR01ES032189 · NIEHS · UNIVERSITY OF LOUISVILLE · PI CAVE, MATTHEW C · 2020 to 2022
$1.9M
NCATS NIH HHS U18 TR003787NCATS NIH HHS UL1 TR002378NHLBI NIH HHS R01 HL125877NHLBI NIH HHS R01 HL160927NIDDK NIH HHS RC2 DK118619NIEHS NIH HHS P30 ES019776NIEHS NIH HHS P30 ES030283NIEHS NIH HHS P42 ES023716NIEHS NIH HHS R01 ES031980NIEHS NIH HHS R01 ES032189NIEHS NIH HHS R21 ES031510NIEHS NIH HHS R35 ES028373NIGMS NIH HHS P20 GM113226
6 · The paper itself

Abstract

Pulmonary arterial hypertension (PAH) prevalence is increasing worldwide, and the prognosis is poor with 5-year survival < 50% in high risk patients. The relationship between metal exposure/essential metal dyshomeostasis and PAH/right ventricular dysfunction is less investigated. The aim of this study is to investigate vegetable consumptions and metal levels between PAH patients and controls. This was a prospective, single center pilot study. Questionnaires were completed by all study subjects (20 PAH patients and 10 healthy controls) on smoking, metal exposure risks, metal supplements, and vegetable consumptions. Blood and urine samples were collected to measure 25 metal levels in blood, plasma, and urine using an X Series II quadrupole inductively coupled plasma mass spectrometry. Statistical analysis was conducted using SAS 9.5 and results with

Indexed as

chromiumcoppermetalpulmonary hypertensionsilver

Identifiers

PMID36824690
PMCPMC9941844
OpenAlexW4320037227

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.