Evidence map›Paper›PMID 36824393›Full record

ArticleInfluenza and other respiratory viruses2023

Epidemiological and clinical characteristics of respiratory syncytial virus and influenza infections in hospitalized children before and during the COVID-19 pandemic in Central China.

Lingshuang Ren, Li Lin, Hua Zhang, Qianli Wang, Yibing Cheng, Qin Liu, Bing Fang, Linsen Xie, Meng Wang, Juan Yang and 5 more

Open access · goldAbstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
12.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

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  14. Clinical characteristics and co-infection analysis of influenza a virus in pediatric respiratory infections: a study based on tNGS technology.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Lingshuang RenSchool of Public Health Fudan University, Key Laboratory of Public Health Safety, Ministry of Education Shanghai China.
Li LinChildren's Hospital Affiliated to Zhengzhou University Henan Children's Hospital Zhengzhou China.
Hua ZhangZhengzhou Central Hospital Affiliated to Zhengzhou University Zhengzhou China.
Qianli WangShanghai Institute of Infectious Disease and Biosecurity Fudan University Shanghai China.
Yibing ChengChildren's Hospital Affiliated to Zhengzhou University Henan Children's Hospital Zhengzhou China.
Qin LiuZhengzhou Central Hospital Affiliated to Zhengzhou University Zhengzhou China.
Bing FangChildren's Hospital Affiliated to Zhengzhou University Henan Children's Hospital Zhengzhou China.
Linsen XieZhengzhou Central Hospital Affiliated to Zhengzhou University Zhengzhou China.
Meng WangChildren's Hospital Affiliated to Zhengzhou University Henan Children's Hospital Zhengzhou China.
Juan YangSchool of Public Health Fudan University, Key Laboratory of Public Health Safety, Ministry of Education Shanghai China.ORCID 0000-0001-5028-2227
Jinxin GuoSchool of Public Health Fudan University, Key Laboratory of Public Health Safety, Ministry of Education Shanghai China.
Tianchen ZhangDivision of Infectious Disease Jiangxi Province Center for Disease Control and Prevention Nanchang China.
Hongkai LianZhengzhou Central Hospital Affiliated to Zhengzhou University Zhengzhou China.
Jiangtao WangChildren's Hospital Affiliated to Zhengzhou University Henan Children's Hospital Zhengzhou China.
Hongjie YuSchool of Public Health Fudan University, Key Laboratory of Public Health Safety, Ministry of Education Shanghai China.ORCID 0000-0002-6335-5648
Fudan University · CNZhengzhou University · CNZhengzhou Central Hospital · CNNanchang Center for Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Globally, the epidemiology of non-SARS-CoV-2 respiratory viruses like respiratory syncytial virus (RSV) and influenza virus was remarkably influenced by the implementation of non-pharmacological interventions (NPIs) during the COVID-19 pandemic. Our study explored the epidemiological and clinical characteristics of pediatric patients hospitalized with RSV or influenza infection before and during the pandemic after relaxation of NPIs in central China. Methods: This hospital-based prospective case-series study screened pediatric inpatients (age ≤ 14 years) enrolled with acute respiratory infections (ARI) for RSV or influenza infection from 2018 to 2021. The changes in positivity rates of viral detection, epidemiological, and clinical characteristics were analyzed and compared. Results: Median ages of all eligible ARI patients from 2018-2019 were younger than those from 2020-2021, so were ages of cases infected with RSV or influenza (RSV: 4.2 months vs. 7.2 months; influenza: 27.3 months vs. 37.0 months). Where the positivity rate for influenza was considerably decreased in 2020-2021 (1.4%, 27/1964) as compared with 2018-2019 (2.9%, 94/3275, P < 0.05), it was increased for RSV (11.4% [372/3275] vs. 13.3% [262/1964], P < 0.05) in the same period. The number of severe cases for both RSV and influenza infection were also decreased in 2020-2021 compared with 2018-2019. Conclusions: The implemented NPIs have had varied impacts on common respiratory viruses. A more effective prevention strategy for RSV infections in childhood is needed.

Indexed as

COVID-19Influenza, HumanRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsRespiratory Tract InfectionsAdolescentChildChild, HospitalizedChinaHumansInfantPandemicschildCOVID‐19hospitalizationinfluenzarespiratory syncytial virus

Identifiers

PMID36824393
PMCPMC9895987
OpenAlexW4319160676

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.