ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2023
Visceral Adiposity Index and Lipid Accumulation Product as Effective Markers of Different Obesity Phenotypes in Korean Adults: A Cross-Sectional Analysis.
Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Lipid Accumulation Product Index as a Marker of Metabolic Syndrome in Women With Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis.Endocrinology, diabetes & metabolism · 2025Pooled it
- Lipid accumulation product (LAP): a key indicator for metabolic dysregulation and inflammatory status in obesity.Scientific reports · 2026Article
- Screening for insulin resistance in children with abdominal obesity: sex-specific performance of TyG index, FGIR, and VAI.Physical activity and nutrition · 2026Article
- Associations Between Dietary Diversity Score and Adiposity Indexes in Obese AdolescentsJournal of clinical research in pediatric endocrinology · 2026Article
- Global diet quality score (GDQS) favorably affects blood pressure, serum lipids, lipid accumulation product and attenuates inflammation among obese individuals.Scientific reports · 2025Article
- Metabolic Risk Profile of Eastern Indian Women with Different Phenotypes of Polycystic Ovary Syndrome.Journal of obstetrics and gynaecology of India · 2025Article
- UCP3 gene variants and obesity in a Pakistani sample population.Scientific reports · 2025Article
- Bridging the gap in obesity research: A consensus statement from the European Society for Clinical Investigation.European journal of clinical investigation · 2025Review
- Visceral and Dysfunctional Adiposity Indices as Predictors of Insulin Resistance and Metabolic Syndrome in Women with Polycystic Ovary Syndrome: A Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2025Article
- Precision Screening for MetS: The Role of Derived Lipid Indicators in Chinese Populations.International journal of endocrinology · 2025Article
- Utility of Anthropometric Indexes for Detecting Metabolic Syndrome in Resource-Limited Regions of Northwestern China: Cross-Sectional Study.JMIR public health and surveillance · 2024Article
- Sex-Specific Cut-Offs of Seven Adiposity Indicators and Their Performance in Predicting Metabolic Syndrome in Arab Adults.Journal of clinical medicine · 2023Article
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Abstract
Purpose: The visceral adiposity index (VAI) and lipid accumulation product (LAP) are useful for assessing visceral obesity. However, these indices were developed for Caucasians, and it is necessary to confirm whether the VAI and LAP are appropriate indicators for identifying obesity phenotypes in Asians. This study investigated whether the VAI and LAP are effective indicators for diagnosing four obesity phenotypes in South Korean adults. Patients and Methods: This cross-sectional study enrolled 23,310 adult participants (age ≥20 years) who had undergone a health checkup at a general hospital in Gyeonggi-do, South Korea from January 2017 to December 2020. VAI and LAP were calculated based on the presented mathematical model according to sex. According to the metabolic health status and presence or absence of obesity, the obesity phenotypes were classified into 4 groups: metabolically healthy non-obese (N=14,240, 61.1%), metabolically unhealthy non-obese (N=477, 2.0%), metabolically healthy obese (MHO; N=6796, 29.2%), and metabolically unhealthy obesity (MUO; N=1797, 7.7%). Results: The receiver operating characteristics curve analysis showed VAI best predicted MUO among the four obesity phenotypes, whereas the LAP showed excellent discriminating ability for the MUO group (area under the curve 0.877, 0.849, and 0.921 and 0.923, 0.907, and 0.954 for all participants, men, and women, respectively). The optimal VAI cutoff values for identifying the MUO group were 1.83 in men and 1.58 in women, and the optimal cutoff values for the LAP were 41.45 in men and 23.83 in women, with a higher value for men. After adjusting for potential confounding factors, the VAI and LAP were associated with an increased risk in the MHO and MUO groups among the obesity phenotypes in both sexes. Conclusion: In South Korean adults, the VAI and LAP are closely related to the MUO phenotype in both sexes and are effective indices for predicting the MUO phenotype.
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