Evidence map›Paper›PMID 36824309›Full record

ArticleBiomaterials and biosystems2021

Polymeric siRNA delivery targeting integrin-β1 could reduce interactions of leukemic cells with bone marrow microenvironment.

Daniel Nisakar Meenakshi Sundaram, Cezary Kucharski, Remant Bahadur Kc, Ibrahim Oğuzhan Tarman, Hasan Uludağ

Open access · goldAbstract read
In one paragraph

Article in Biomaterials and biosystems, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Daniel Nisakar Meenakshi SundaramFaculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.
Cezary KucharskiDepartment of Chemical and Materials Engineering, University of Alberta, Edmonton, AB, Canada.
Remant Bahadur KcDepartment of Chemical and Materials Engineering, University of Alberta, Edmonton, AB, Canada.
Ibrahim Oğuzhan TarmanFaculty of Science, Bilkent University, Ankara, Turkey.
Hasan UludağFaculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.
University of Alberta · CABilkent University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uncontrolled proliferation of the myeloid cells due to

Indexed as

Chronic myeloid leukemiaFibronectin bindingIntegrin-β1PolyethyleneimineRNAisiRNA delivery

Identifiers

PMID36824309
PMCPMC9934419
OpenAlexW3183822763

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.