Evidence map›Paper›PMID 36824195›Full record

ReviewFrontiers in plant science2023

CRISPR-Cas: A robust technology for enhancing consumer-preferred commercial traits in crops.

Vipasha Verma, Akhil Kumar, Mahinder Partap, Meenakshi Thakur, Bhavya Bhargava

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in plant science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
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  8. CRISPR/Cas system and its application in the diagnosis of animal infectious diseases.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Review
  9. Review
  10. Article
  11. Article
  12. Review
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  17. Article
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  20. Plants' Response to Abiotic Stress: Mechanisms and Strategies.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Vipasha VermaFloriculture Laboratory, Agrotechnology Division, Council of Scientific and Industrial Research (CSIR) -Institute of Himalayan Bioresource Technology (IHBT), Palampur, India.
Akhil KumarFloriculture Laboratory, Agrotechnology Division, Council of Scientific and Industrial Research (CSIR) -Institute of Himalayan Bioresource Technology (IHBT), Palampur, India.
Mahinder PartapFloriculture Laboratory, Agrotechnology Division, Council of Scientific and Industrial Research (CSIR) -Institute of Himalayan Bioresource Technology (IHBT), Palampur, India.
Meenakshi ThakurFloriculture Laboratory, Agrotechnology Division, Council of Scientific and Industrial Research (CSIR) -Institute of Himalayan Bioresource Technology (IHBT), Palampur, India.
Bhavya BhargavaFloriculture Laboratory, Agrotechnology Division, Council of Scientific and Industrial Research (CSIR) -Institute of Himalayan Bioresource Technology (IHBT), Palampur, India.
Council of Scientific and Industrial Research · INInstitute of Himalayan Bioresource Technology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The acceptance of new crop varieties by consumers is contingent on the presence of consumer-preferred traits, which include sensory attributes, nutritional value, industrial products and bioactive compounds production. Recent developments in genome editing technologies provide novel insight to identify gene functions and improve the various qualitative and quantitative traits of commercial importance in plants. Various conventional as well as advanced gene-mutagenesis techniques such as physical and chemical mutagenesis, CRISPR-Cas9, Cas12 and base editors are used for the trait improvement in crops. To meet consumer demand, breakthrough biotechnologies, especially CRISPR-Cas have received a fair share of scientific and industrial interest, particularly in plant genome editing. CRISPR-Cas is a versatile tool that can be used to knock out, replace and knock-in the desired gene fragments at targeted locations in the genome, resulting in heritable mutations of interest. This review highlights the existing literature and recent developments in CRISPR-Cas technologies (base editing, prime editing, multiplex gene editing, epigenome editing, gene delivery methods) for reliable and precise gene editing in plants. This review also discusses the potential of gene editing exhibited in crops for the improvement of consumer-demanded traits such as higher nutritional value, colour, texture, aroma/flavour, and production of industrial products such as biofuel, fibre, rubber and pharmaceuticals. In addition, the bottlenecks and challenges associated with gene editing system, such as off targeting, ploidy level and the ability to edit organelle genome have also been discussed.

Indexed as

commercial traitsCRISPR-Cas based genome editinggene deliveryplant biotechnologytargeted mutation

Identifiers

PMID36824195
PMCPMC9941649
OpenAlexW4319440308

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.