Evidence map›Paper›PMID 36824164›Full record

ArticleBiomaterials and biosystems2022

Vascular tissue engineering from human adipose tissue: fundamental phenotype of its resident microvascular endothelial cells and stromal/stem cells.

Jeremy A Antonyshyn, Meghan J McFadden, Anthony O Gramolini, Stefan O P Hofer, J Paul Santerre

Open access · goldAbstract read
In one paragraph

Article in Biomaterials and biosystems, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jeremy A AntonyshynInstitute of Biomedical Engineering, University of Toronto, Toronto, Canada.
Meghan J McFaddenInstitute of Biomedical Engineering, University of Toronto, Toronto, Canada.
Anthony O GramoliniTranslational Biology and Engineering Program, Ted Rogers Centre for Heart Research, Toronto, Canada.
Stefan O P HoferDivision of Plastic, Reconstructive, and Aesthetic Surgery, University of Toronto, Toronto, Canada.
J Paul SanterreInstitute of Biomedical Engineering, University of Toronto, Toronto, Canada.
University of Toronto · CAUniversity Health Network · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adipose tissue is an abundant, accessible, and uniquely dispensable source of cells for vascular tissue engineering. Despite its intrinsic endothelial cells, considerable effort is directed at deriving endothelium from its resident stem and progenitor cells. Here, we investigate the composition of human adipose tissue and characterize the phenotypes of its constituent cells in order to help ascertain their potential utility for vascular tissue engineering. Unsupervised clustering based on cell-surface protein signatures failed to detect CD45

Indexed as

Adipose tissueAdipose tissue-derived stromal/stem cellEndothelial cellEndothelial progenitor cellProteomicsVascular tissue engineering

Identifiers

PMID36824164
PMCPMC9934493
OpenAlexW4223628585

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.