Evidence map›Paper›PMID 36824162›Full record

ArticleBiomaterials and biosystems2022

Comparison of human amniotic membrane and collagen nerve wraps around sciatic nerve reverse autografts in a rat model.

Erin M Wolfe, Sydney A Mathis, Natalia de la Olivo Muñoz, Steven A Ovadia, Zubin J Panthaki

2 registry-linked trialsAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomaterials and biosystems, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06470087 nacompletednot on this mapstarted 2024, after this paper: background citation

A Randomized Controlled Clinical Trial Comparing High Purity Type-I Collagen-based Skin Substitute to Dehydrated Human Amnion/Chorion Membrane in the Treatment of Diabetic Foot Ulcers

TypeinterventionalSponsorAdichunchanagiri Institute of Medical Sciences, B G NagaraRan2024 to 2024Enrolled28ConditionsDiabetic Foot Ulcer (DFU)ArmsSOC and Type-I Collagen-based Skin Substitute, SOC and Human Amnion/Chorion Membrane
NCT07046403 nacompletednot on this mapstarted 2025, after this paper: background citation

A Multicentric Randomized Controlled Clinical Trial Comparing the Use of High Purity Type-I Collagen-Based Skin Substitute vs. Dehydrated Human Amnion/Chorion Membrane in the Treatment of Diabetic Foot Ulcers

TypeinterventionalSponsorAdichunchanagiri Institute of Medical Sciences, B G NagaraRan2025 to 2025Enrolled120ConditionsDiabetic Foot Ulcer (DFU)ArmsHigh Purity Type-I Collagen-based Skin Substitute and SOC, Dehydrated Human Amnion / Chorion Membrane and SOC
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Ongoing Clinical Challenges in Nerve Surgery (Nerve SPACE 2025).Journal of hand surgery global online · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Nerve Coaptation in 2023: Adjuncts to Nerve Repair Beyond Suture.Journal of hand surgery global online · 2024
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Erin M WolfeDepartment of Surgery, Division of Plastic and Reconstructive Surgery, University of Miami Miller School of Medicine, Miami, Florida USA.
Sydney A MathisDepartment of Surgery, Division of Plastic and Reconstructive Surgery, University of Miami Miller School of Medicine, Miami, Florida USA.
Natalia de la Olivo MuñozDepartment of Neurological Surgery, The Neuroscience Program, Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, Miami, Florida USA.
Steven A OvadiaDepartment of Surgery, Division of Plastic and Reconstructive Surgery, University of Miami Miller School of Medicine, Miami, Florida USA.
Zubin J PanthakiDepartment of Surgery, Division of Plastic and Reconstructive Surgery, University of Miami Miller School of Medicine, Miami, Florida USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human amniotic membrane (hAM) and collagen nerve wraps are biomaterials that have been investigated as therapies for improving outcomes of peripheral nerve regeneration; however, their efficacy has not been compared. The purpose of this study is to compare the efficacy of collagen and human amniotic membrane nerve wraps in a rodent sciatic nerve reverse autograft model. Lewis rats (

Indexed as

Amniotic membraneAxonal regenerationCollagenFibrosisFunctional recoveryNerve autograftPeripheral nerve injuryRegeneration

Identifiers

PMID36824162
PMCPMC9934491

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.