Evidence map›Paper›PMID 36823958›Full record

ArticlePhysiological reports2023

Effect of exercise-induced bronchoconstriction on the configuration of the maximal expiratory flow-volume curve in adults with asthma.

Oksana Klimenko, Peter Luu, Paolo Dominelli, Nathan Noggle, Gregory Petrics, Hans Christian Haverkamp

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Oksana KlimenkoDepartment of Nutrition and Exercise Physiology, Washington State University-Spokane Health Sciences, Elson S. Floyd College of Medicine, Spokane, Washington, USA.
Peter LuuDepartment of Nutrition and Exercise Physiology, Washington State University-Spokane Health Sciences, Elson S. Floyd College of Medicine, Spokane, Washington, USA.
Paolo DominelliDepartment of Kinesiology and Health Sciences, University of Waterloo, Waterloo, Ontario, Canada.
Nathan NoggleDepartment of Nutrition and Exercise Physiology, Washington State University-Spokane Health Sciences, Elson S. Floyd College of Medicine, Spokane, Washington, USA.
Gregory PetricsDepartment of Mathematics, Northern Vermont University-Johnson, Johnson, Vermont, USA.
Hans Christian HaverkampDepartment of Nutrition and Exercise Physiology, Washington State University-Spokane Health Sciences, Elson S. Floyd College of Medicine, Spokane, Washington, USA.ORCID 0000-0001-8207-318X
Washington State University Spokane · USNorthern Vermont University · USUniversity of Waterloo · CA

Funding

Vermont INBRE Administrative Supplement 2024 AWD 118P20GM103449 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI CHRISTOPHER S FRANCKLYN · 2012 to 2026
$58.4M
NIGMS NIH HHS P20 GM103449
6 · The paper itself

Abstract

We determined the effect of exercise-induced bronchoconstriction (EIB) on the shape of the maximal expiratory flow-volume (MEFV) curve in asthmatic adults. The slope-ratio index (SR) was used to quantitate the shape of the MEFV curve. We hypothesized that EIB would be accompanied by increases in SR and thus increased curvilinearity of the MEFV curve. Adult asthmatic ( n  = 10) and non-asthmatic control subjects ( n  = 9) cycled for 6-8 min at 85% of peak power. Following exercise, subjects remained on the ergometer and performed a maximal forced exhalation every 2 min for a total 20 min. In each MEFV curve, the slope-ratio index (SR) was calculated in 1% volume increments beginning at peak expiratory flow (PEF) and ending at 20% of forced vital capacity (FVC). Baseline spirometry was lower in asthmatics compared to control subjects (FEV

Indexed as

Asthma, Exercise-InducedMaximal Expiratory Flow-Volume CurvesAdultAsthmaBronchoconstrictionExerciseExhalationForced Expiratory VolumeHumansasthmabronchoconstrictionexerciseflow-volume curvemaximal expiration

Identifiers

PMID36823958
PMCPMC9950550
OpenAlexW4321748866

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.