SynthesisClinical and experimental dental research2023
A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent teeth.
Synthesis in Clinical and experimental dental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06797882 (The Effectiveness of Silver Diamine Fluoride), which is not on this map. Cited by 15 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effectiveness of Silver Diamine Fluoride (SDF) in the Prevention of Early Enamel Caries Among Patients With Fixed Orthodontic Appliances: A Randomised Controlled Trial
Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Do systematic reviews of non- and micro-invasive treatment for caries lesions in children and adolescents adhere to the PRISMA reporting guidelines? A meta-research.Evidence-based dentistry · 2026Pooled it
- The Potential of Silver Diamine Fluoride in Non-Operative Management of Dental Caries in Primary Teeth: A Systematic Review.Medicina (Kaunas, Lithuania) · 2024Pooled it
- A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent teeth.Clinical and experimental dental research · 2023Pooled it
- SDF vs resin sealants in preventing caries among high-risk children: a 2-year randomized trial.Brazilian dental journal · 2026Trial
- Efficacy of topical strategies to prevent the onset of root caries lesions: an in vitro study.Odontology · 2026Article
- Current Perspectives on Management Approaches for Molar Incisor Hypomineralization: Preliminary findings from the National Dental Practice-Based Research Network.The Journal of clinical pediatric dentistry · 2026Article
- The effect of using silver diamine fluoride at two different times on the microshear bond strength of adhesives to sound and caries-affected dentin.Dental research journal · 2026Article
- Comparison of Patient Acceptance and Caregiver Satisfaction of Glass-Ionomer Cement vs. Silver Fluoride/Potassium Iodide Application to Manage Molar Incisor Hypomineralisation Hypersensitivity Immediately and After 12 Weeks.Clinics and practice · 2025Article
- The Effect of Silver Diamine Fluoride Combined with Potassium Iodide and Sodium Fluoride on the Remineralisation of Hydroxyapatite.Oral health & preventive dentistry · 2025Article
- Knowledge, Practices, and Attitudes Towards Silver Diamine Fluoride Therapy Among Dentists and Students in Southeastern Spain.Dentistry journal · 2025Article
- Revolutionizing adult oral care: Silver diamine fluoride's minimally invasive role.Bioinformation · 2025Article
- Parental satisfaction and acceptance of silver diamine fluoride treatment for molar incisor hypomineralisation in pediatric dentistry: a cross-sectional study.Scientific reports · 2024Article
- The pharmacokinetics of 38% silver diamine fluoride in healthy children with dental caries: a quasi-experimental study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2023Article
- Article
- Level of acceptance and parental perception of silver diamine fluoride treatment in a peruvian school. A cross-sectional study.Revista cientifica odontologica (Universidad Cientifica del Sur)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe objective of this review is to assess the available literature systematically related to the effect of silver diamine fluoride (SDF) for the management of occlusal and root carious lesions in permanent teeth regardless of age. MATERIALS AND
methodsThis systematic review was conducted according to the Cochrane Handbook for Systematic Reviews of Interventions and Preferred Reporting Items for Systematic Review and Meta-Analyses statement. A literature search was performed using PubMed/MEDLINE, Cochrane Central Register of Controlled Trials, Web of Science, DOAJ, and Open Gray with no language restrictions up to December 2022. Three reviewers critically assessed the studies for eligibility. Any disputes between the reviewers were handled by a fourth independent reviewer. The quality assessment and data extraction of the studies were performed.
resultsA total of 2176 studies were screened. The titles and abstracts of the studies were then reviewed (n = 346), and 52 studies met the search criteria. Following the full-text review, 11 studies investigated the effect of SDF against other treatments such as chlorhexidine, sodium fluoride, ammonium bifluoride, tricalcium silicate paste, casein phosphopeptide amorphous calcium phosphate, glass ionomer cement (GIC) combined with fluoride varnish, resin-modified GIC, and atraumatic restorative treatment were assessed.
conclusionsWithin the limitations of this review, the use of SDF is promising with high preventative fractions in permanent teeth of children and older populations when compared to other topical applications such as dental varnish containing sodium fluoride.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.