Evidence map›Paper›PMID 36823623›Full record

ArticleBMC health services research2023

Process control: simply a matter of efficiency or of survival and costs? A single-centre quality improvement project in living donor renal transplant.

Filippo Paoletti, Vittori Giorgio, Adel Jaser, Natalia Romina Zanoni, Walter Ricciardi, Franco Citterio, Antonio Giulio De Belvis

Open access · goldAbstract read
In one paragraph

Article in BMC health services research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Filippo PaolettiClinical Pathways and Outcome Evaluation Unit, Fondazione Policlinico Universitario A.Gemelli IRCSS, Rome, Italy. filippopaoletti.an@gmail.com.
Vittori GiorgioSocietà Italiana di Ginecologia e Ostetricia, Rome, Italy.
Adel JaserLean Program Unit, IREN, Turin, Italy.
Natalia Romina ZanoniDepartment of Medical and Surgical Sciences, Urology, Nephrology and Renal Transplant Area, Fondazione Policlinico Universitario A.Gemelli IRCSS, Rome, Italy.
Walter RicciardiSection of Hygiene, Department of Health Science and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy.
Franco Citterio *Department of Medical and Surgical Sciences, Urology, Nephrology and Renal Transplant Area, Fondazione Policlinico Universitario A.Gemelli IRCSS, Rome, Italy.
Antonio Giulio De Belvis *Clinical Pathways and Outcome Evaluation Unit, Fondazione Policlinico Universitario A.Gemelli IRCSS, Rome, Italy.
Agostino Gemelli University Polyclinic · ITSocietà Italiana di Cardiologia · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRising incidence and prevalence of end-stage renal disease is a worldwide concern for sustainability of healthcare systems and societies. Living donor renal transplant [LDRT] provides highest health achievements and cost containment than any alternative form of renal replacement therapy. Nonetheless, about 25% of potential LDRTs are missed for causes directly related with inadequate timing in donor assessment. Our quality improvement (QI) project implement process control tools and strategy aiming at reducing total evaluation time for donor candidates and minimizing dialysis exposure for intended recipients, which are the two main determinants of clinical outcomes and costs.

methodsThe study includes patients who underwent donor nephrectomy between January 1, 2017 and December 31, 2021. Six Sigma DMAIC approach was adopted to assess Base Case performance (Jan2017-Jun2019) and to design and implement our QI project. Study of current state analysis focused on distribution of time intervals within the assessment process, analysis of roles and impacts of involved healthcare providers and identification of targets of improvement. Improved Scenario (Jul2019-Dec2021) was assessed in terms of total lead time reduction, total pre-transplantation dialysis exposure and costs reduction, and increase in pre-emptive transplantations. The study was reported following SQUIRE 2.0 Guidelines for QI projects.

resultsStudy population includes 63 patients, 37 in Base Case and 26 in Improved Scenario. Total lead time reduced from a median of 293 to 166 days and this in turn reduced pre-transplantation dialysis exposure and costs by 45%. Rate of potential pre-emptive donors' loss changes from 44% to 27%.

conclusionsLean methodology is an effective tool to improve quality and efficiency of healthcare processes, in the interest of patients, healthcare professionals and payers.

Indexed as

Kidney Failure, ChronicKidney TransplantationHumansLiving DonorsQuality ImprovementRenal DialysisClinical governanceLean methodologyLiving donorQuality improvementRenal transplantation

Identifiers

PMID36823623
PMCPMC9947903
OpenAlexW4321595860

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.