Evidence map›Paper›PMID 36823412›Full record

ArticleInternational journal of legal medicine2023

Assessing retinal hemorrhages with non-invasive post-mortem fundus photographs in sudden unexpected death in infancy.

Jean-Baptiste Ducloyer, Cloé Scherpereel, Thomas Goronflot, Guylène Le Meur, Pierre Lebranchu, Frédérique Jossic, Virginie Scolan, Mathilde Ducloyer

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Article in International journal of legal medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Jean-Baptiste DucloyerNantes Université, CHU Nantes, service d'ophtalmologie, Nantes, France. jeanbaptiste.ducloyer@chu-nantes.fr.ORCID http://orcid.org/0000-0002-1306-1908
Cloé ScherpereelCHU Grenoble, service de médecine légale, Grenoble, France.
Thomas GoronflotNantes Université, CHU Nantes, Pôle Hospitalo-Universitaire 11: Santé Publique, Clinique des données, INSERM, CIC 1413, F-44000, Nantes, France.
Guylène Le MeurNantes Université, CHU Nantes, service d'ophtalmologie, Nantes, France.
Pierre LebranchuNantes Université, CHU Nantes, service d'ophtalmologie, Nantes, France.
Frédérique JossicInstitut d'histopathologie (IHP Group), Angers, France.
Virginie ScolanCHU Grenoble, service de médecine légale, Grenoble, France.
Mathilde DucloyerNantes Université, CHU Nantes, service de médecine légale, Nantes, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn the case of sudden unexpected death in infancy (SUDI), eye examination is systematic to detect retinal hemorrhages (RH) that are a crucial hallmark for abusive head trauma (AHT). The aim of this study is to assess the ability of non-invasive post-mortem fundus photographs (PMFP) to detect RH in case of SUDI.

methodsBicentric retrospective analysis of consecutive cases of SUDI under 2 years of age were managed by two French SUDI referral centers with PMFP by RetCam (Clarity Medical Systems USA). PMFP were reviewed randomly, twice, by three independent ophthalmologists blinded for clinical data.

resultsThirty cases (60 eyes) were included. Median age was 3.5 months (interquartile [1.6; 6.0]). No child died of AHT. Image quality was sufficient to assert presence or absence of RH in 50 eyes (83%). Sufficient quality rate was significantly higher when the post-mortem interval was inferior to 18 h (91%, 42/46) as opposed to over 18 h (57%, 8/14, p=0.0096). RH were found in six eyes (10%), four children (13%), with excellent inter and intra-raters' concordance (Cohen's Kappa from 0.81 [0.56-1.00] to 1.00 [1.00-1.00]).

conclusionPMFP can detect RH in case of SUDI and is a relevant systematic screening test to be carried out as soon as the deceased child arrives in the hospital. It can decrease the need of eye removal for pathological examination, but further studies are needed to define the best decision algorithm.

Indexed as

Craniocerebral TraumaSudden Infant DeathAutopsyHumansInfantRetinal HemorrhageRetrospective StudiesAbusive head traumaPost-mortemRetCamRetinal hemorrhagesSudden unexpected death in infancySUDI

Identifiers

PMID36823412
PMCPMC10085933

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