Evidence map›Paper›PMID 36823407›Full record

ArticleNature immunology2023

Macrophages set the bar for acute pain sensitivity.

Sara Hakim, Clifford J Woolf

Abstract readComment
PubMed Publisher
In one paragraph

Article in Nature immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Emerging role of macrophages in neuropathic pain.Journal of orthopaedic translation · 2025
    Review
  3. Role of M1/M2 macrophages in pain modulation.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Sara HakimF.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.
Clifford J WoolfF.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA. clifford.woolf@childrens.harvard.edu.ORCID http://orcid.org/0000-0002-6636-3897

Funding

The Role of Sciatic Nerve Inflammation in Diabetic NeuropathyF31NS127357 · NINDS · HARVARD MEDICAL SCHOOL · PI HAKIM, SARA · 2022 to 2023
$76k
NINDS NIH HHS F31 NS127357
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acute PainHumansMacrophages

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.