Evidence map›Paper›PMID 36823167›Full record

ArticleeNeuro2023

Investigating the Role of Rhodopsin

Deepak Poria, Alexander V Kolesnikov, Tae Jun Lee, David Salom, Krzysztof Palczewski, Vladimir J Kefalov

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eNeuro, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Deepak PoriaDepartment of Ophthalmology, Gavin Herbert Eye Institute, University of California, Irvine, CA 92697.
Alexander V KolesnikovDepartment of Ophthalmology, Gavin Herbert Eye Institute, University of California, Irvine, CA 92697.
Tae Jun LeeDepartment of Ophthalmology and Visual Sciences, Washington University School of Medicine, Saint Louis, MO 63110.
David SalomDepartment of Ophthalmology, Gavin Herbert Eye Institute, University of California, Irvine, CA 92697.
Krzysztof PalczewskiDepartment of Ophthalmology, Gavin Herbert Eye Institute, University of California, Irvine, CA 92697.
Vladimir J KefalovDepartment of Ophthalmology, Gavin Herbert Eye Institute, University of California, Irvine, CA 92697 vkefalov@uci.edu.
University of California System · USUniversity of California, Irvine · USWashington University in St. Louis · US

Funding

The complex role of phosphodiesterase 6 in rod photoreceptor health and functionR01EY030873 · NEI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Krzysztof Palczewski · 2020 to 2026
$3.5M
Opsin signaling in mammalian rod photoreceptorsR01EY030912 · NEI · WASHINGTON UNIVERSITY · PI KEFALOV, VLADIMIR JIVKOV, PALCZEWSKI, KRZYSZTOF · 2020 to 2023
$1.6M
NEI NIH HHS R01 EY030873NEI NIH HHS R01 EY030912
6 · The paper itself

Abstract

Rhodopsin is the critical receptor molecule which enables vertebrate rod photoreceptor cells to detect a single photon of light and initiate a cascade of molecular events leading to visual perception. Recently, it has been suggested that the F45L mutation in the transmembrane helix of rhodopsin disrupts its dimerization

Indexed as

Retinal Rod Photoreceptor CellsRhodopsinAnimalsDark AdaptationMiceMutationRetinaRhodopsinelectroretinogramphototransductionretinal degenerationrhodopsinrods

Identifiers

PMID36823167
PMCPMC9997694
OpenAlexW4321607695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.