Evidence map›Paper›PMID 36823160›Full record

ArticleNPJ vaccines2023

Immunogenicity and protective efficacy of GBP510/AS03 vaccine against SARS-CoV-2 delta challenge in rhesus macaques.

Catherine Jacob-Dolan, Jingyou Yu, Katherine McMahan, Victoria Giffin, Abishek Chandrashekar, Amanda J Martinot, Tochi Anioke, Olivia C Powers, Kevin Hall, David Hope and 14 more

Open access · goldAbstract read
In one paragraph

Article in NPJ vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  7. Molecular mechanisms of SARS-CoV-2 entry: implications for biomedical strategies.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Advances in virus-like particle-based SARS-CoV-2 vaccines.Frontiers in cellular and infection microbiology · 2024
    Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 4 institutions in 1 country.

Catherine Jacob-Dolan *Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.ORCID http://orcid.org/0000-0001-6641-0342
Jingyou Yu *Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.ORCID http://orcid.org/0000-0002-0775-6623
Katherine McMahan *Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.
Victoria Giffin *Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.
Abishek Chandrashekar *Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.
Amanda J MartinotTufts Cummings School of Veterinary Medicine, North Grafton, MA, 01536, USA.
Tochi AniokeCenter for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.
Olivia C PowersCenter for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.
Kevin HallCenter for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.
David HopeCenter for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.ORCID http://orcid.org/0000-0001-5654-1744
Jessica MillerCenter for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.
Nichole P HachmannCenter for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.ORCID http://orcid.org/0000-0002-2100-8461
Benjamin ChungCenter for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.
Sarah GardnerCenter for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.
Daniel SellersCenter for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.ORCID http://orcid.org/0000-0002-8815-9459
Julia BarrettCenter for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.ORCID http://orcid.org/0000-0002-5857-3632
Mark G LewisBioqual, Rockville, MD, 20852, USA.ORCID http://orcid.org/0000-0001-7852-0135
Hanne AndersenBioqual, Rockville, MD, 20852, USA.ORCID http://orcid.org/0000-0003-1103-9608
Harry KleanthousBill and Melinda Gates Foundation, Seattle, WA, 98109, USA.
Ki-Woen SeoDepartment of Research and Development, SK bioscience 310 Pangyo-ro, Bundang-gu, Seongnam-si, Gyeonggi-do, Republic of Korea.
Su Jeen LeeDepartment of Research and Development, SK bioscience 310 Pangyo-ro, Bundang-gu, Seongnam-si, Gyeonggi-do, Republic of Korea.
Yong Wook ParkDepartment of Research and Development, SK bioscience 310 Pangyo-ro, Bundang-gu, Seongnam-si, Gyeonggi-do, Republic of Korea.
Hun KimDepartment of Research and Development, SK bioscience 310 Pangyo-ro, Bundang-gu, Seongnam-si, Gyeonggi-do, Republic of Korea.
Dan H BarouchCenter for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA. dbarouch@bidmc.harvard.edu.ORCID http://orcid.org/0000-0001-5127-4659
Beth Israel Deaconess Medical Center · USBioqual · USGates Foundation · USNew England Disabled Sports · US

Funding

Single-Cell Analysis of the HIV/SIV ReservoirR01AI149670 · NIAID · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BAROUCH, DAN H., SHALEK, ALEX K · 2020 to 2024
$4.6M
6 · The paper itself

Abstract

Despite the availability of several effective SARS-CoV-2 vaccines, additional vaccines will be required for optimal global vaccination. In this study, we investigate the immunogenicity and protective efficacy of the GBP510 protein subunit vaccine adjuvanted with AS03, which has recently been authorized for marketing in South Korea under the trade name SKYCovione

Identifiers

PMID36823160
PMCPMC9947939
OpenAlexW4321597347

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.