Evidence map›Paper›PMID 36822507›Full record

ArticleThe Journal of pediatrics2023

Leveraging Serologic Testing to Identify Children at Risk For Post-Acute Sequelae of SARS-CoV-2 Infection: An Electronic Health Record-Based Cohort Study from the RECOVER Program.

Asuncion Mejias, Julia Schuchard, Suchitra Rao, Tellen D Bennett, Ravi Jhaveri, Deepika Thacker, L Charles Bailey, Dimitri A Christakis, Nathan M Pajor, Hanieh Razzaghi and 2 more

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in The Journal of pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 1 country.

Asuncion MejiasDivision of Infectious Diseases, Department of Pediatrics, Nationwide Children's Hospital and The Ohio State University, Columbus, OH. Electronic address: asuncion.mejias@nationwidechildrens.org.
Julia SchuchardApplied Clinical Research Center, Children's Hospital of Philadelphia, Philadelphia, PA.
Suchitra RaoDepartment of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO.
Tellen D BennettDepartment of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO.
Ravi JhaveriDivision of Infectious Diseases, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL.
Deepika ThackerDivision of Cardiology, Nemours Children's Health, Wilmington, DE.
L Charles BaileyApplied Clinical Research Center, Children's Hospital of Philadelphia, Philadelphia, PA.
Dimitri A ChristakisCenter for Child Health, Behavior and Development, Seattle Children's Hospital, Seattle, WA.
Nathan M PajorDivision of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, OH.
Hanieh RazzaghiApplied Clinical Research Center, Children's Hospital of Philadelphia, Philadelphia, PA.
Christopher B ForrestApplied Clinical Research Center, Children's Hospital of Philadelphia, Philadelphia, PA.
Grace M LeeDepartment of Pediatrics (Infectious Diseases), Stanford University School of Medicine, Stanford, CA.
Children's Hospital of Philadelphia · USChildren's Hospital Colorado · USCincinnati Children's Hospital Medical Center · USLurie Children's Hospital · USNationwide Children's Hospital · USNemours Children's Health System · USSeattle Children's Hospital · USStanford University · US

Funding

OTA-21-015A Post-Acute Sequelae of SARS-CoV-2 Infection Initiative: NYU Langone Health Clinical Science Core, Data Resource Core, and PASC Biorepository CoreOT2HL161847 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI GROSS, RACHEL SHARON, HORWITZ, LEORA · 2021 to 2025
$651.0M
6 · The paper itself

Abstract

Using an electronic health record-based algorithm, we identified children with Coronavirus disease 2019 (COVID-19) based exclusively on serologic testing between March 2020 and April 2022. Compared with the 131 537 polymerase chain reaction-positive children, the 2714 serology-positive children were more likely to be inpatients (24% vs 2%), to have a chronic condition (37% vs 24%), and to have a diagnosis of multisystem inflammatory syndrome in children (23% vs <1%). Identification of children who could have been asymptomatic or paucisymptomatic and not tested is critical to define the burden of post-acute sequelae of severe acute respiratory syndrome coronavirus 2 infection in children.

Indexed as

COVID-19Antibodies, ViralChildCohort StudiesCOVID-19 TestingDisease ProgressionElectronic Health RecordsHumansPost-Acute COVID-19 SyndromeSARS-CoV-2Systemic Inflammatory Response SyndromeAntibodies, Viralanti-N antibodiesanti-S antibodieschronic COVID-19 syndromeCOVID-19 serologylate sequelae of COVID-19long COVIDlong-haul COVID-19long-term COVID-19PEDSnetpost-acute COVID-19post-acute sequelae of COVID-19post-acute sequelae of SARS-CoV-2 infectionpost–COVID-19 syndrome

Identifiers

PMID36822507
PMCPMC9943558
OpenAlexW4321438360

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.