Evidence map›Paper›PMID 36822229›Full record

ArticleThe Thoracic and cardiovascular surgeon2024

Simultaneous Aortic and Pulmonary Valve Replacement in Repaired Congenital Heart Disease.

Dmitry Bobylev, Klea Hysko, Murat Avsar, Tomislav Cvitkovic, Elena Petena, Samir Sarikouch, Mechthild Westhoff Bleck, Georg Hansmann, Axel Haverich, Alexander Horke

Open access · hybridAbstract read
In one paragraph

Article in The Thoracic and cardiovascular surgeon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Dmitry BobylevDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Niedersachsen, Germany.ORCID 0000-0002-3961-8348
Klea HyskoDepartment of Pediatric Cardiology and Pediatric Intensive Care, Hannover Medical School, Hannover, Niedersachsen, Germany.
Murat AvsarDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Niedersachsen, Germany.
Tomislav CvitkovicDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Niedersachsen, Germany.
Elena PetenaDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Niedersachsen, Germany.
Samir SarikouchDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Niedersachsen, Germany.
Mechthild Westhoff BleckDepartment of Pediatric Cardiology and Pediatric Intensive Care, Hannover Medical School, Hannover, Niedersachsen, Germany.
Georg HansmannDepartment of Pediatric Cardiology and Pediatric Intensive Care, Hannover Medical School, Hannover, Niedersachsen, Germany.
Axel HaverichDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Niedersachsen, Germany.
Alexander HorkeDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Niedersachsen, Germany.
Medizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPatients with congenital heart disease frequently require surgical or percutaneous interventional valve replacement after initial congenital heart defect (CHD) repair. In some of these patients, simultaneous replacement of both semilunar valves is necessary, resulting in increased procedural complexity, morbidity, and mortality. In this study, we analyze the outcomes of simultaneous aortic and pulmonary valve replacements following multiple surgical interventions for CHD.

methodsThis was a retrospective study of 24 patients who after initial repair of CHD underwent single-stage aortic and pulmonary valve replacement at our institution between 2003 and 2021.

resultsThe mean age of the patients was 28 ± 13 years; the mean time since the last surgery was 15 ± 11 years. Decellularized valved homografts (DVHs) were used in nine patients, and mechanical valves were implanted in seven others. In eight patients, DVHs, biological, and mechanical valves were implanted in various combinations. The mean cardiopulmonary bypass time was 303 ± 104 minutes, and aortic cross-clamp time was 152 ± 73 minutes. Two patients died at 12 and 16 days postoperatively. At a maximum follow-up time of 17 years (mean 7 ± 5 years), 95% of the surviving patients were categorized as New York Heart Association heart failure class I.

conclusionSingle-stage aortic and pulmonary valve replacement after initial repair of CHD remains challenging with substantial perioperative mortality (8.3%). Nevertheless, long-term survival and clinical status at the latest follow-up were excellent. The valve type had no relevant impact on the postoperative course. The selection of the valves for implantation should take into account operation-specific factors-in particular reoperability-as well as the patients' wishes.

Indexed as

Aortic ValveHeart Defects, CongenitalHeart Valve ProsthesisHeart Valve Prosthesis ImplantationPulmonary ValveAdolescentAdultBioprosthesisChildFemaleHeart Valve DiseasesHumansMaleMiddle AgedPostoperative ComplicationsProsthesis Design

Identifiers

PMID36822229
PMCPMC11288660
OpenAlexW4321605531

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.