Evidence map›Paper›PMID 36822142›Full record

ReviewCurrent opinion in neurobiology2023

Drosophila glia take shape to sculpt the nervous system.

Megan M Corty, Jaeda Coutinho-Budd

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Regulating glial morphogenesis: insights fromFrontiers in cell and developmental biology · 2026
    Review
  5. Frontiers in cell and developmental biology · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. CaActa physiologica (Oxford, England) · 2025
    Article
  10. Article
  11. Review
  12. Homemade: building the structure of the neurogenic niche.Frontiers in cell and developmental biology · 2023
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Megan M CortyVollum Institute, Oregon Health & Science University, Portland, OR, USA. Electronic address: https://twitter.com/@megancphd.
Jaeda Coutinho-BuddDepartment of Neuroscience, University of Virginia, Charlottesville, VA, USA. Electronic address: Jaeda.coutinho-budd@virginia.edu.

Funding

Mechanisms of Glial Interactions and Function at Neuronal Cell BodiesR01NS121101 · NINDS · UNIVERSITY OF VIRGINIA · PI COUTINHO-BUDD, JAEDA · 2021 to 2025
$2.0M
Retooling innate immunity: An investigation of TLR-mediated glial priming across lifespanR01NS120689 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI BROIHIER, HEATHER · 2021 to 2025
$2.0M
How do non-myelinating glia ensheath axons?R01NS112215 · NINDS · OREGON HEALTH & SCIENCE UNIVERSITY · PI FREEMAN, MARC R · 2019 to 2023
$1.7M
NINDS NIH HHS R01 NS112215NINDS NIH HHS R01 NS120689NINDS NIH HHS R01 NS121101
6 · The paper itself

Abstract

The importance of glial cells has become increasingly apparent over the past 20 years, yet compared to neurons we still know relatively little about these essential cells. Most critical glial cell functions are conserved in Drosophila glia, often using the same key molecular players as their vertebrate counterparts. The relative simplicity of the Drosophila nervous system, combined with a vast array of powerful genetic tools, allows us to further dissect the molecular composition and functional roles of glia in ways that would be much more cumbersome or not possible in higher vertebrate systems. Importantly, Drosophila genetics allow for in vivo manipulation, and their transparent body wall enables in vivo imaging of glia in intact animals throughout early development. Here we discuss recent advances in Drosophila glial development detailing how these cells take on their mature morphologies and interact with neurons to perform their important functional roles in the nervous system.

Indexed as

DrosophilaDrosophila ProteinsAnimalsNeurogliaNeuronsVertebratesDrosophila ProteinsAstrocytesCortex gliaDevelopmentDrosophilaEnsheathing gliaGliaMorphogenesisPerineurial gliaSubperineurial gliaWrapping glia

Identifiers

PMID36822142
PMCPMC10023329

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.