Evidence map›Paper›PMID 36821828›Full record

ArticleChemical research in toxicology2023

Evaluation of Per- and Polyfluoroalkyl Substances (PFAS)

Kelly E Carstens, Theresa Freudenrich, Kathleen Wallace, Seline Choo, Amy Carpenter, Marci Smeltz, Matthew S Clifton, W Matthew Henderson, Ann M Richard, Grace Patlewicz and 3 more

Abstract read
In one paragraph

Article in Chemical research in toxicology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Review of in vitro approaches for assessing the toxicity of chemical stressors across diverse physiological systems.Toxicological sciences : an official journal of the Society of Toxicology · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Combined Effects of PFAS and Metals on Cognitive Function.Environments (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Bioactivity of the ubiquitous tire preservative 6PPD and degradant, 6PPD-quinone in fish- and mammalian-based assays.Toxicological sciences : an official journal of the Society of Toxicology · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kelly E CarstensCenter for Computational Toxicology and Exposure, ORD, US EPA, Research Triangle Park, North Carolina 27711, United States.ORCID 0000-0002-1746-5379
Theresa FreudenrichCenter for Computational Toxicology and Exposure, ORD, US EPA, Research Triangle Park, North Carolina 27711, United States.
Kathleen WallaceCenter for Computational Toxicology and Exposure, ORD, US EPA, Research Triangle Park, North Carolina 27711, United States.
Seline ChooOak Ridge Institute for Science and Education (ORISE), Oak Ridge, Tennessee 37830, United States.
Amy CarpenterOak Ridge Institute for Science and Education (ORISE), Oak Ridge, Tennessee 37830, United States.
Marci SmeltzCenter for Environmental Measurement and Modeling, ORD, US EPA, Research Triangle Park, North Carolina 27711, United States.
Matthew S CliftonCenter for Environmental Measurement and Modeling, ORD, US EPA, Research Triangle Park, North Carolina 27711, United States.
W Matthew HendersonCenter for Environmental Measurement and Modeling, ORD, US EPA, Research Triangle Park, North Carolina 27711, United States.
Ann M RichardCenter for Computational Toxicology and Exposure, ORD, US EPA, Research Triangle Park, North Carolina 27711, United States.ORCID 0000-0003-2116-2300
Grace PatlewiczCenter for Computational Toxicology and Exposure, ORD, US EPA, Research Triangle Park, North Carolina 27711, United States.
Barbara A WetmoreCenter for Computational Toxicology and Exposure, ORD, US EPA, Research Triangle Park, North Carolina 27711, United States.ORCID 0000-0002-6878-5348
Katie Paul FriedmanCenter for Computational Toxicology and Exposure, ORD, US EPA, Research Triangle Park, North Carolina 27711, United States.ORCID 0000-0002-2710-1691
Timothy ShaferCenter for Computational Toxicology and Exposure, ORD, US EPA, Research Triangle Park, North Carolina 27711, United States.

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

Per- and polyfluoroalkyl substances (PFAS) are a diverse set of commercial chemicals widely detected in humans and the environment. However, only a limited number of PFAS are associated with epidemiological or experimental data for hazard identification. To provide developmental neurotoxicity (DNT) hazard information, the work herein employed DNT new approach methods (NAMs) to generate

Indexed as

FluorocarbonsNeurotoxicity SyndromesApoptosisHumansNeuronal OutgrowthNeuronsFluorocarbons

Identifiers

PMID36821828
PMCPMC10249374

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.