Evidence map›Paper›PMID 36821761›Full record

Trial reportJournal of the American Geriatrics Society2023

The association of vitamin D supplementation and serum vitamin D levels with physical activity in older adults: Results from a randomized trial.

Jennifer A Schrack, Yurun Cai, Jacek K Urbanek, Amal A Wanigatunga, Christine M Mitchell, Edgar R Miller, Jack M Guralnik, Stephen P Juraschek, Erin D Michos, David L Roth and 1 more

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American Geriatrics Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Jennifer A SchrackDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Yurun CaiDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Jacek K UrbanekCenter on Aging and Health, Johns Hopkins University and Medical Institutions, Baltimore, Maryland, USA.
Amal A WanigatungaDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0002-5763-5184
Christine M MitchellDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0002-8211-281X
Edgar R MillerWelch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University and Medical Institutions, Baltimore, Maryland, USA.
Jack M GuralnikDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Stephen P JuraschekDivision of General Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School Teaching Hospital, Boston, Massachusetts, USA.ORCID 0000-0003-4168-2696
Erin D MichosWelch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University and Medical Institutions, Baltimore, Maryland, USA.ORCID 0000-0002-5547-5084
David L RothCenter on Aging and Health, Johns Hopkins University and Medical Institutions, Baltimore, Maryland, USA.
Lawrence J AppelDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Johns Hopkins University · USBeth Israel Deaconess Medical Center · USUniversity of Maryland, Baltimore · US

Funding

QAQC Johns Hopkins Institute for Clinical and Translational ResearchUL1TR003098 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2019 to 2023
$57.7M
Research BaseP30DK072488 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D · 2005 to 2019
$17.3M
Vitamin D Supplements to Prevent Falls in Older Adults: A Dose-Response TrialU01AG047837 · NIA · JOHNS HOPKINS UNIVERSITY · PI APPEL, LAWRENCE JOHN · 2014 to 2019
$9.5M
RENAL DISEASE EPIDEMIOLOGY TRAINING GRANTT32DK007732 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI CREWS, DEIDRA CANDICE · 1995 to 2024
$7.7M
Vitamin D, Subclinical Cardiovascular Disease, and Orthostatic Hypotension in Older AdultsK23HL135273 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI JURASCHEK, STEPHEN P · 2017 to 2021
$1.1M
NCATS NIH HHS UL1 TR003098NHLBI NIH HHS K23 HL135273NHLBI NIH HHS K23HL135273NIA NIH HHS U01 AG047837NIA NIH HHS U01AG047837NIDDK NIH HHS P30 DK072488NIDDK NIH HHS T32 DK007732NIDDK NIH HHS T32DK007732
6 · The paper itself

Abstract

backgroundTo assess whether vitamin D

methodsSecondary data analyses of STURDY (Study to Understand Fall Reduction and Vitamin D in You), a response-adaptive randomized clinical trial. Participants included 571 adults aged 70 years and older with baseline serum 25(OH)D levels of 10-29 ng/mL and elevated fall risk, who wore a wrist accelerometer at baseline and at least one follow-up visit and were randomized to receive: 200 IU/day (control), 1000, 2000, or 4000 IU/day of vitamin D

resultsIn adjusted models, physical activity quantities declined (p < 0.001) and became more fragmented, or "broken up", (p = 0.017) over time. Supplementation with vitamin D

conclusionIn low-functioning older adults with serum 25(OH)D levels 10-29 ng/mL, vitamin D

Indexed as

Dietary SupplementsVitamin D DeficiencyAgedAged, 80 and overCholecalciferolDouble-Blind MethodExerciseHumansVitamin DVitaminsCholecalciferolVitamin DVitaminsaccelerometryphysical activityserum vitamin Dvitamin D supplementation

Identifiers

PMID36821761
PMCPMC10363216
OpenAlexW4321607151

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.