Evidence map›Paper›PMID 36821567›Full record

ArticlePloS one2023

Deep learning for the diagnosis of mesial temporal lobe epilepsy.

Kyoya Sakashita, Yukinori Akiyama, Tsukasa Hirano, Ayaka Sasagawa, Masayasu Arihara, Tomoyoshi Kuribara, Satoko Ochi, Rei Enatsu, Takeshi Mikami, Nobuhiro Mikuni

Abstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kyoya SakashitaDepartment of Neurosurgery, Sapporo Medical University, Sapporo, Japan.ORCID 0000-0001-7284-1106
Yukinori AkiyamaDepartment of Neurosurgery, Sapporo Medical University, Sapporo, Japan.
Tsukasa HiranoDepartment of Neurosurgery, Sapporo Medical University, Sapporo, Japan.
Ayaka SasagawaDepartment of Neurosurgery, Sapporo Medical University, Sapporo, Japan.
Masayasu AriharaDepartment of Neurosurgery, Sapporo Medical University, Sapporo, Japan.ORCID 0000-0002-8969-1172
Tomoyoshi KuribaraDepartment of Neurosurgery, Sapporo Medical University, Sapporo, Japan.
Satoko OchiDepartment of Neurosurgery, Sapporo Medical University, Sapporo, Japan.
Rei EnatsuDepartment of Neurosurgery, Sapporo Medical University, Sapporo, Japan.
Takeshi MikamiDepartment of Neurosurgery, Sapporo Medical University, Sapporo, Japan.
Nobuhiro MikuniDepartment of Neurosurgery, Sapporo Medical University, Sapporo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to enable the automatic detection of the hippocampus and diagnose mesial temporal lobe epilepsy (MTLE) with the hippocampus as the epileptogenic area using artificial intelligence (AI). We compared the diagnostic accuracies of AI and neurosurgical physicians for MTLE with the hippocampus as the epileptogenic area.

methodIn this study, we used an AI program to diagnose MTLE. The image sets were processed using a code written in Python 3.7.4. and analyzed using Open Computer Vision 4.5.1. The deep learning model, which was a fine-tuned VGG16 model, consisted of several layers. The diagnostic accuracies of AI and board-certified neurosurgeons were compared.

resultsAI detected the hippocampi automatically and diagnosed MTLE with the hippocampus as the epileptogenic area on both T2-weighted imaging (T2WI) and fluid-attenuated inversion recovery (FLAIR) images. The diagnostic accuracies of AI based on T2WI and FLAIR data were 99% and 89%, respectively, and those of neurosurgeons based on T2WI and FLAIR data were 94% and 95%, respectively. The diagnostic accuracy of AI was statistically higher than that of board-certified neurosurgeons based on T2WI data (p = 0.00129).

conclusionThe deep learning-based AI program is highly accurate and can diagnose MTLE better than some board-certified neurosurgeons. AI can maintain a certain level of output accuracy and can be a reliable assistant to doctors.

Indexed as

Deep LearningEpilepsy, Temporal LobeArtificial IntelligenceHippocampusHumansMagnetic Resonance Imaging

Identifiers

PMID36821567
PMCPMC9949622

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.