Evidence map›Paper›PMID 36821506›Full record

ArticleRadiographics : a review publication of the Radiological Society of North America, Inc2023

Sophia R O'Brien, Christine E Edmonds, Shannon M Lanzo, Joanna K Weeks, David A Mankoff, Austin R Pantel

Abstract read
PubMed Publisher
In one paragraph

Article in Radiographics : a review publication of the Radiological Society of North America, Inc, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Utilization ofAdvances in radiation oncology · 2026
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  3. Real-world application ofEuropean journal of nuclear medicine and molecular imaging · 2026
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  5. Uptake Patterns of [Cancers · 2026
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  9. Dual-Tracer Imaging on a Long-Axial-Field-of-View PET: A Proof-of-Principle Study with [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
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  13. False-positive 16α-[European journal of nuclear medicine and molecular imaging · 2025
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  16. Evaluation of [Molecular therapy : the journal of the American Society of Gene Therapy · 2024
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  17. Dynamic whole-body [EJNMMI research · 2024
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  18. Review
  19. Invited Commentary: A Recently Approved PET Imaging Agent to Guide Breast Cancer Therapy.Radiographics : a review publication of the Radiological Society of North America, Inc · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Sophia R O'BrienFrom the Department of Radiology, Division of Breast Imaging (S.R.O., C.E.E.) and Division of Nuclear Medicine Imaging and Therapy (S.R.O., S.M.L., J.K.W., D.A.M., A.R.P.), Hospital of the University of Pennsylvania, 3400 Spruce St, 1 Silverstein-Radiology Administration, Philadelphia, PA 19104.ORCID 0000-0002-2685-101X
Christine E EdmondsFrom the Department of Radiology, Division of Breast Imaging (S.R.O., C.E.E.) and Division of Nuclear Medicine Imaging and Therapy (S.R.O., S.M.L., J.K.W., D.A.M., A.R.P.), Hospital of the University of Pennsylvania, 3400 Spruce St, 1 Silverstein-Radiology Administration, Philadelphia, PA 19104.
Shannon M LanzoFrom the Department of Radiology, Division of Breast Imaging (S.R.O., C.E.E.) and Division of Nuclear Medicine Imaging and Therapy (S.R.O., S.M.L., J.K.W., D.A.M., A.R.P.), Hospital of the University of Pennsylvania, 3400 Spruce St, 1 Silverstein-Radiology Administration, Philadelphia, PA 19104.
Joanna K WeeksFrom the Department of Radiology, Division of Breast Imaging (S.R.O., C.E.E.) and Division of Nuclear Medicine Imaging and Therapy (S.R.O., S.M.L., J.K.W., D.A.M., A.R.P.), Hospital of the University of Pennsylvania, 3400 Spruce St, 1 Silverstein-Radiology Administration, Philadelphia, PA 19104.ORCID 0000-0002-2736-108X
David A MankoffFrom the Department of Radiology, Division of Breast Imaging (S.R.O., C.E.E.) and Division of Nuclear Medicine Imaging and Therapy (S.R.O., S.M.L., J.K.W., D.A.M., A.R.P.), Hospital of the University of Pennsylvania, 3400 Spruce St, 1 Silverstein-Radiology Administration, Philadelphia, PA 19104.ORCID 0000-0002-6971-5413
Austin R PantelFrom the Department of Radiology, Division of Breast Imaging (S.R.O., C.E.E.) and Division of Nuclear Medicine Imaging and Therapy (S.R.O., S.M.L., J.K.W., D.A.M., A.R.P.), Hospital of the University of Pennsylvania, 3400 Spruce St, 1 Silverstein-Radiology Administration, Philadelphia, PA 19104.ORCID 0000-0001-8649-9970

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the United States, breast cancer is the second leading cause of cancer death in all women and the leading cause of cancer death in Black women. The breast cancer receptor profile, assessed with immunohistochemical staining of tissue samples, allows prediction of outcomes and direction of patient treatment. Approximately 80% of newly diagnosed breast cancers are hormone receptor (HR) positive, which is defined as estrogen receptor (ER) and/or progesterone receptor (PR) positive. Patients with ER-positive disease can be treated with therapies targeting the ER; however, the assessment of ER expression with immunohistochemical staining of biopsy specimens has several limitations including sampling error, false-negative results, challenging or inaccessible biopsy sites, and the inability to synchronously and serially assess all metastatic sites to identify spatial and/or temporal ER heterogeneity. In May 2020, after decades of research, the U.S. Food and Drug Administration approved the PET radiotracer fluorine 18 (

Indexed as

Breast NeoplasmsEstradiolBiopsyFemaleHumansPositron-Emission TomographyReceptors, EstrogenEstradiolReceptors, Estrogen

Identifiers

PMID36821506

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.