ArticleCell reports2023
Locomotion-induced gain of visual responses cannot explain visuomotor mismatch responses in layer 2/3 of primary visual cortex.
Article in Cell reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 30 citations in OpenAlex.
- Article
- Ecological Visual Processing in the Mouse.Annual review of neuroscience · 2026Review
- Article
- Is the impact of spontaneous movements on early visual cortex species specific?Trends in neurosciences · 2025Review
- Computational model of layer 2/3 in mouse primary visual cortex explains observed visuomotor mismatch response.Journal of computational neuroscience · 2024Article
- Article
- Modeling circuit mechanisms of opposing cortical responses to visual flow perturbations.PLoS computational biology · 2024Article
- The locus coeruleus broadcasts prediction errors across the cortex to promote sensorimotor plasticity.eLife · 2023Article
- Redefining sensorimotor mismatch selectivity in the visual cortex.Cell reports · 2023Article
- Computational components of visual predictive coding circuitry.Frontiers in neural circuits · 2023Review
- Efficient Temporal Coding in the Early Visual System: Existing Evidence and Future Directions.Frontiers in computational neuroscience · 2022Review
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this work is to provide a comment on a recent paper by Muzzu and Saleem (2021), which claims that visuomotor mismatch responses in mouse visual cortex can be explained by a locomotion-induced gain of visual halt responses. Our primary concern is that without directly comparing these responses with mismatch responses, the claim that one response can explain the other appears difficult to uphold, more so because previous work finds that a uniform locomotion-induced gain cannot explain mismatch responses. To support these arguments, we analyze layer 2/3 calcium imaging datasets and show that coupling between visual flow and locomotion greatly enhances mismatch responses in an experience-dependent manner compared with halts in non-coupled visual flow. This is consistent with mismatch responses representing visuomotor prediction errors. Thus, we conclude that while feature selectivity might contribute to mismatch responses in mouse visual cortex, it cannot explain these responses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.