Evidence map›Paper›PMID 36821075›Full record

ArticleJournal of veterinary internal medicine2023

Onchocerca sp. in an imported Zangersheide gelding causing suspensory ligament desmitis.

Kara A Brown, Amy L Johnson, Susan J Bender, Thomas J Nolan, Bianca Pfisterer, JoAnn Slack, Elinor Willis, Emily K Rule

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of veterinary internal medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Detection ofTransboundary and emerging diseases · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Kara A BrownDepartment of Clinical Studies, New Bolton Center, University of Pennsylvania School of Veterinary Medicine, Kennett Square, Pennsylvania 19348, USA.ORCID https://orcid.org/0000-0003-3027-4304
Amy L JohnsonDepartment of Clinical Studies, New Bolton Center, University of Pennsylvania School of Veterinary Medicine, Kennett Square, Pennsylvania 19348, USA.ORCID https://orcid.org/0000-0003-2507-0040
Susan J BenderDepartment of Pathobiology, New Bolton Center, University of Pennsylvania School of Veterinary Medicine, Kennett Square, Pennsylvania 19348, USA.
Thomas J NolanDepartment of Pathobiology, Ryan Veterinary Hospital, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania 19104, USA.
Bianca PfistererDepartment of Pathobiology, New Bolton Center, University of Pennsylvania School of Veterinary Medicine, Kennett Square, Pennsylvania 19348, USA.
JoAnn SlackDepartment of Clinical Studies, New Bolton Center, University of Pennsylvania School of Veterinary Medicine, Kennett Square, Pennsylvania 19348, USA.
Elinor WillisDepartment of Pathobiology, New Bolton Center, University of Pennsylvania School of Veterinary Medicine, Kennett Square, Pennsylvania 19348, USA.
Emily K RuleDepartment of Clinical Studies, New Bolton Center, University of Pennsylvania School of Veterinary Medicine, Kennett Square, Pennsylvania 19348, USA.ORCID https://orcid.org/0000-0003-4648-7902
University of Pennsylvania · USHospital of the University of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 5-year-old imported Zangersheide gelding was evaluated for SC swellings over both forelimbs and lameness localized to the distal metacarpus. Ultrasound examination of the SC masses was compatible with verminous granulomas. Linear hyperechoic foci were present within the suspensory ligament branches of both forelimbs, suggestive of ligamentous parasitic infiltrates. A diagnosis of onchocerciasis was confirmed on biopsy of a SC mass. The gelding was treated with ivermectin and a tapering course of PO dexamethasone but was eventually euthanized. Necropsy confirmed the presence of SC eosinophilic granulomas and degenerative suspensory ligament desmitis, both with intralesional nematodes. Given the location and appearance of the nematode, a diagnosis of Onchocerca sp., most likely O. reticulata, was made. Onchocerciasis should be included as a differential diagnosis for multifocal suspensory ligament desmitis with these sonographic characteristics when paired with SC masses in imported European Warmbloods.

Indexed as

ArthritisHorse DiseasesMuscular DiseasesOnchocerciasisAnimalsHorsesLigamentsMaleOnchocercainfectiousparasiteultrasoundWarmblood

Identifiers

PMID36821075
PMCPMC10061162
OpenAlexW4321611181

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.