Evidence map›Paper›PMID 36821003›Full record

ArticleMikrochimica acta2023

Ratiometric SERS-based assay with "sandwich" structure for detection of serotonin.

Min Fan, Sirui Han, Qian Huang, Jingbo Chen, Shangyuan Feng, Yudong Lu, Ruiyun You

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Min FanCollege of Chemistry and Materials Science, Fujian Provincial Key Laboratory of Advanced, Materials Oriented Chemical Engineering, Fujian Key Laboratory of Polymer Materials, Engineering Research Center of Industrial Biocatalysis, Fujian Province Higher Education Institutes, Fujian Normal University, Fuzhou, 350007, China.
Sirui HanCollege of Chemistry and Materials Science, Fujian Provincial Key Laboratory of Advanced, Materials Oriented Chemical Engineering, Fujian Key Laboratory of Polymer Materials, Engineering Research Center of Industrial Biocatalysis, Fujian Province Higher Education Institutes, Fujian Normal University, Fuzhou, 350007, China.
Qian HuangCollege of Chemistry and Materials Science, Fujian Provincial Key Laboratory of Advanced, Materials Oriented Chemical Engineering, Fujian Key Laboratory of Polymer Materials, Engineering Research Center of Industrial Biocatalysis, Fujian Province Higher Education Institutes, Fujian Normal University, Fuzhou, 350007, China.
Jingbo ChenDepartment of Oncology Shengli Clinical Medical College of Fujian Medical , University Fujian Provincial Hospital, Fuzhou, 350001, Fujian, China. 13635294192@163.com.
Shangyuan FengKey Laboratory of Optoelectronic Science and Technology for Medicine of Ministry of Education, Fujian Provincial Key Laboratory of Photonics Technology, Fujian Normal University, Fuzhou, 350117, Fujian, China.
Yudong LuCollege of Chemistry and Materials Science, Fujian Provincial Key Laboratory of Advanced, Materials Oriented Chemical Engineering, Fujian Key Laboratory of Polymer Materials, Engineering Research Center of Industrial Biocatalysis, Fujian Province Higher Education Institutes, Fujian Normal University, Fuzhou, 350007, China.
Ruiyun YouCollege of Chemistry and Materials Science, Fujian Provincial Key Laboratory of Advanced, Materials Oriented Chemical Engineering, Fujian Key Laboratory of Polymer Materials, Engineering Research Center of Industrial Biocatalysis, Fujian Province Higher Education Institutes, Fujian Normal University, Fuzhou, 350007, China. youruiyun@fjnu.edu.cn.
Fujian Normal University · CNFujian Provincial Hospital · CN

Funding

Fujian Provincial Department of Science and Technology guiding Project 2020Y0019The National Natural Science Foundation of China 61975031The program for Industry University Cooperation Project of Fujian Province 2020Y4006Youth and middle-aged backbone talents training project of Fujian Health Commission 2020GGA003
6 · The paper itself

Abstract

A ratiometric nanoensemble-functionalized Surface-Enhanced Raman Spectroscopy (SERS) chip is proposed and an ultrasensitive "sandwich" structure introduced for the detection of 5-HT to achieve early diagnosis of colon cancer. The SERS-based chip contains core-shell SERS active substrates coded by different Raman tags with Raman-silent region peaks (Au@EBP@Au NR arrays and Au@MBN@Ag NPs) and then identify-function molecule modification to construct the "sandwich" structure (Au@EBP@Au NR arrays/5-HT/Au@MBN@Ag NPs). Au@EBP@Au NR arrays showed excellent SERS performance, including good uniformity with an RSD of 5.53% and an enhancement factor (EF) of 2.13 × 10

Indexed as

Metal NanoparticlesSerotoninGoldHumansSilverSpectrum Analysis, RamanGoldSerotoninSilver5-HydroxytryptamineAu@EBP@Au arraysAu@MBN@Ag NPsBiologically Raman-silent regionColon cancerRatiometric SERS-based probe

Identifiers

PMID36821003
OpenAlexW4321600267

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.