Evidence map›Paper›PMID 36820643›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2023

Influenza A(H5N1) detection in two asymptomatic poultry farm workers in Spain, September to October 2022: suspected environmental contamination.

Esteban Aznar, Inmaculada Casas, Alejandro González Praetorius, María José Ruano Ramos, Francisco Pozo, María José Sierra Moros, María Victoria García Rivera, Azucena Sánchez Sánchez, Elena García Villacieros, Gabriela Saravia and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
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  8. Article
  9. Avian influenza overview September-December 2024.EFSA journal. European Food Safety Authority · 2025
    Article
  10. Preparedness, prevention and control related to zoonotic avian influenza.EFSA journal. European Food Safety Authority · 2025
    Article
  11. Article
  12. Avian influenza overview June-September 2024.EFSA journal. European Food Safety Authority · 2024
    Article
  13. Article
  14. Article
  15. Interpretation of molecular detection of avian influenza A virus in respiratory specimens collected from live bird market workers in Dhaka, Bangladesh: infection or contamination?International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2023
    Article
  16. Avian influenza, new aspects of an old threat.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023
    Article
  17. Avian influenza overview December 2022 - March 2023.EFSA journal. European Food Safety Authority · 2023
    Article
  18. Letter to the Editor: Knowledge gap in assessing the risk of a human pandemic via mammals' infection with highly pathogenic avian influenza A(H5N1).Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023
    Article
  19. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Esteban AznarCoordinating Centre for Health Alerts and Emergencies, Ministry of Health, Madrid, Spain.
Inmaculada CasasInfluenza and Respiratory Unit, National Centre for Microbiology, Instituto de Salud Carlos III, Madrid, Spain.
Alejandro González PraetoriusMicrobiology laboratory, Hospital General Universitario de Guadalajara, Guadalajara, Spain.
María José Ruano RamosLaboratorio Central de Veterinaria, Ministerio de Agricultura, Pesca y Alimentación, Algete, Spain.
Francisco PozoInfluenza and Respiratory Unit, National Centre for Microbiology, Instituto de Salud Carlos III, Madrid, Spain.
María José Sierra MorosCoordinating Centre for Health Alerts and Emergencies, Ministry of Health, Madrid, Spain.
María Victoria García RiveraConsejería de Sanidad de la Junta de Castilla-La Mancha, Dirección General de Salud Pública, Departamento de Epidemiología, Toledo, Spain.
Azucena Sánchez SánchezLaboratorio Central de Veterinaria, Ministerio de Agricultura, Pesca y Alimentación, Algete, Spain.
Elena García VillacierosSubdirección General de Sanidad e Higiene Animal y Trazabilidad, Ministerio de Agricultura, Pesca y Alimentación, Madrid, Spain.
Gabriela SaraviaCoordinating Centre for Health Alerts and Emergencies, Ministry of Health, Madrid, Spain.
María Iglesias-CaballeroInfluenza and Respiratory Unit, National Centre for Microbiology, Instituto de Salud Carlos III, Madrid, Spain.
Elena Román MarcosConsejería de Sanidad de la Junta de Castilla-La Mancha, Dirección General de Salud Pública, Departamento de Epidemiología, Toledo, Spain.
Lucía García San MiguelCoordinating Centre for Health Alerts and Emergencies, Ministry of Health, Madrid, Spain.
Ministry of Health · ESInstituto de Salud Carlos III · ESMinisterio de Agricultura, Pesca y Alimentación · ESHospital Universitario de Guadalajara · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In autumn 2022, the Spanish Influenza National Reference Laboratory (NRL) confirmed the detection of influenza A(H5N1) in samples from two asymptomatic workers linked to an outbreak in a poultry farm in Spain. Nasopharyngeal swabs were taken according to a national screening protocol for exposed workers. Absence of symptoms, low viral load and negative serology in both workers suggested environmental contamination. These findings motivated an update of the early detection strategy specifying timing and sampling conditions in asymptomatic exposed persons.

Indexed as

Influenza A Virus, H5N1 SubtypeInfluenza, HumanInfluenza in BirdsPoultry DiseasesAnimalsDisease OutbreaksFarmersHumansPoultrySpainasymptomatichighly pathogenic avian influenzaHPAI A(H5N1)humanoutbreakSpain

Identifiers

PMID36820643
PMCPMC9951258
OpenAlexW4321611860

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.