Evidence map›Paper›PMID 36820406›Full record

ArticleOxidative medicine and cellular longevity2023

PW06 Triggered Fas-FADD to Induce Apoptotic Cell Death In Human Pancreatic Carcinoma MIA

Yi-Ping Huang, Te-Chun Hsia, Chun-An Yeh, Yi-Shih Ma, Sheng-Yao Hsu, Yi-Chung Liu, Ping-Chiang Lyu, Kuang-Chi Lai, Shu-Fen Peng, Jin-Cherng Lien and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxidative medicine and cellular longevity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Research Progress of Regulatory Cell Death in Coronary Microembolization.International journal of medical sciences · 2025
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Yi-Ping HuangDepartment of Physiology, School of Medicine, China Medical University, Taichung 404333, Taiwan.ORCID https://orcid.org/0000-0003-0775-9880
Te-Chun HsiaDepartment of Medical Research, China Medical University Hospital, Taichung 404333, Taiwan.ORCID https://orcid.org/0000-0003-4297-9918
Chun-An YehDepartment of Physiology, School of Medicine, China Medical University, Taichung 404333, Taiwan.
Yi-Shih MaSchool of Chinese Medicine for Post-Baccalaureate, I-Shou University, Kaohsiung 84001, Taiwan.
Sheng-Yao HsuDepartment of Ophthalmology, An Nan Hospital, China Medical University, Tainan 709, Taiwan.ORCID https://orcid.org/0000-0002-3000-0664
Yi-Chung LiuInstitute of Population Health Sciences, National Health Research Institutes, Miaoli 350, Taiwan.ORCID https://orcid.org/0000-0003-1437-0363
Ping-Chiang LyuInstitute of Bioinformatics and Structural Biology, National Tsing-Hua University, Hsinchu 300044, Taiwan.ORCID https://orcid.org/0000-0002-6824-543X
Kuang-Chi LaiDepartment of Medical Laboratory Science and Biotechnology, College of Medical Technology, Chung Hwa University of Medical Technology, Tainan, Taiwan.ORCID https://orcid.org/0000-0001-7580-1222
Shu-Fen PengDepartment of Biological Science and Technology, China Medical University, Taichung 406040, Taiwan.ORCID https://orcid.org/0000-0002-1792-0474
Jin-Cherng LienSchool of Pharmacy, China Medical University, Taichung 406040, Taiwan.ORCID https://orcid.org/0000-0002-1211-0245
Wen-Tsong HsiehChinese Medicine Research Center, China Medical University, Taichung 404333, Taiwan.ORCID https://orcid.org/0000-0002-2330-8898
China Medical University · TWChung Hwa University of Medical Technology · TWE-Da Hospital · TWNational Health Research Institutes · TWNational Tsing Hua University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cancer has higher incidence and mortality rates worldwide. PW06 [(E)-3-(9-ethyl-9H-carbazol-3-yl)-1-(2,5-dimethoxyphenyl) prop-2-en-1-one] is a carbazole derivative containing chalcone moiety which was designed for inhibiting tumorigenesis in human pancreatic cancer. This study is aimed at investigating PW06-induced anticancer effects in human pancreatic cancer MIA PaCa-2 cells

Indexed as

Antineoplastic AgentsPancreatic NeoplasmsApoptosisApoptosis Regulatory ProteinsCaspase 3Caspase 8Caspase 9CaspasesCell Line, TumorFas-Associated Death Domain Proteinfas ReceptorHumansAntineoplastic AgentsApoptosis Regulatory ProteinsCaspase 3Caspase 8Caspase 9CaspasesFADD protein, humanFas-Associated Death Domain ProteinFAS protein, humanfas Receptor

Identifiers

PMID36820406
PMCPMC9938777
OpenAlexW4320034698

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.