Evidence map›Paper›PMID 36820081›Full record

ArticleInfection and drug resistance2023

Evaluation of Tigecycline Utilization and Trends in Antibacterial Resistance from 2018 to 2021 in a Comprehensive Teaching Hospital in China.

Hong Zhou, Xiangyu Sun, Shaocheng Lyu, Xiaojia Yu, Ran Li, Huaguang Wang, Zhuoling An

Abstract read
In one paragraph

Article in Infection and drug resistance, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Tigecycline and Hypoglycemia, When and How?The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2024
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hong Zhou *Pharmacy Department of Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People's Republic of China.ORCID 0000-0001-8183-2391
Xiangyu Sun *Drug and Equipment Department, Beijing Chaoyang Emergency Medical Rescuing Center, Beijing, People's Republic of China.
Shaocheng LyuDepartment of Hepatobiliary Surgery, Beijing Chao Yang Hospital, Capital Medical University, Beijing, People's Republic of China.
Xiaojia YuPharmacy Department of Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People's Republic of China.
Ran LiDepartment of Infectious Diseases and Clinical Microbiology, Capital Medical University, Beijing, People's Republic of China.
Huaguang WangPharmacy Department of Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People's Republic of China.
Zhuoling AnPharmacy Department of Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Tigecycline, the first glycylcycline antibiotic, which was widely used for off-label indications because of its broad-spectrum antibacterial activity. This study evaluated the indications for clinical use of tigecycline, clinical and microbiological effectiveness, factors associated with in hospital mortality, and bacterial resistance. Methods: This retrospective study evaluated all inpatients who received tigecycline treatment for >72 hours between January 2018 and December 2021 in a comprehensive teaching hospital in China. The evaluation included indications, administration regimen, etiology, efficacy and so on. Univariate and multivariate analyses were used to evaluate the risk factors for all-cause mortality. Results: There were 203 patients treated with tigecycline. Tigecycline was commonly prescribed for off-label indications (83.25%, 169/203), and hospital-acquired pneumonia ranked first (79.29%, 134/169). The most common pathogen was Conclusion: Although detection of

Indexed as

antimicrobial resistanceclinical prognosisoff-label indicationrationality of medication

Identifiers

PMID36820081
PMCPMC9938701

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.