Evidence map›Paper›PMID 36819938›Full record

ArticleBrain communications2023

Tinnitus and distress: an electroencephalography classification study.

Andrea Piarulli, Sven Vanneste, Idan Efim Nemirovsky, Sivayini Kandeepan, Audrey Maudoux, Angelo Gemignani, Dirk De Ridder, Andrea Soddu

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review and Perspective on Brain Bases of Tinnitus.Journal of the Association for Research in Otolaryngology : JARO · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 6 countries.

Andrea PiarulliDepartment of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa 56124, Italy.
Sven VannesteTrinity College Institute for Neuroscience & School of Psychology, Trinity College, Dublin D02 PN40, Ireland.ORCID https://orcid.org/0000-0003-1513-5752
Idan Efim NemirovskyWestern Institute for Neuroscience, Physics & Astronomy Department, University of Western Ontario, London, ON N6A 3K7, Canada.
Sivayini KandeepanDepartment of Physics, University of Sri Jayewardenepura, Nugegoda 10250, Sri Lanka.
Audrey MaudouxRobert Debré University Hospital, APHP, Paris 75019, France.
Angelo GemignaniDepartment of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa 56124, Italy.
Dirk De RidderBrain Research Center for Innovative and Interdisciplinary Neuromodulation and Department of Neurosurgery, University Hospital, Antwerp 2650, Belgium.
Andrea SodduWestern Institute for Neuroscience, Physics & Astronomy Department, University of Western Ontario, London, ON N6A 3K7, Canada.ORCID https://orcid.org/0000-0001-6833-745X
University of Pisa · ITWestern University · CAAssistance Publique – Hôpitaux de Paris · FRTrinity College Dublin · IEUniversity of Otago · NZUniversity of Sri Jayewardenepura · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There exist no objective markers for tinnitus or tinnitus disorders, which complicates diagnosis and treatments. The combination of EEG with sophisticated classification procedures may reveal biomarkers that can identify tinnitus and accurately differentiate different levels of distress experienced by patients. EEG recordings were obtained from 129 tinnitus patients and 142 healthy controls. Linear support vector machines were used to develop two classifiers: the first differentiated tinnitus patients from controls, while the second differentiated tinnitus patients with low and high distress levels. The classifier for healthy controls and tinnitus patients performed with an average accuracy of 96 and 94% for the training and test sets, respectively. For the distress classifier, these average accuracies were 89 and 84%. Minimal overlap was observed between the features of the two classifiers. EEG-derived features made it possible to accurately differentiate healthy controls and tinnitus patients as well as low and high distress tinnitus patients. The minimal overlap between the features of the two classifiers indicates that the source of distress in tinnitus, which could also be involved in distress related to other conditions, stems from different neuronal mechanisms compared to those causing the tinnitus pathology itself.

Indexed as

distressmachine learningsufferingtinnitus

Identifiers

PMID36819938
PMCPMC9927883
OpenAlexW4318765997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.