Evidence map›Paper›PMID 36819853›Full record

ArticleChemical science2023

Cu(ii)-BODIPY photosensitizer for CAIX overexpressed cancer stem cell therapy.

Hyo Sung Jung, Seyoung Koo, Miae Won, Seeun An, Haebeen Park, Jonathan L Sessler, Jiyou Han, Jong Seung Kim

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Review
  3. Copper Complexes: Main Mechanisms as Anticancer Agents.Molecules (Basel, Switzerland) · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Fluorescent small molecule donors.Chemical Society reviews · 2024
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Hyo Sung JungDepartment of Biological Sciences, Hyupsung University Hwasung-si 18330 Korea hs0101j@gmail.com hanjiyou12@hanmail.net.ORCID https://orcid.org/0000-0003-2018-8226
Seyoung KooDepartment of Chemistry, Korea University Seoul 02841 Korea jongskim@korea.ac.kr.
Miae WonDepartment of Chemistry, Korea University Seoul 02841 Korea jongskim@korea.ac.kr.
Seeun AnDepartment of Biological Sciences, Hyupsung University Hwasung-si 18330 Korea hs0101j@gmail.com hanjiyou12@hanmail.net.
Haebeen ParkDepartment of Biological Sciences, Hyupsung University Hwasung-si 18330 Korea hs0101j@gmail.com hanjiyou12@hanmail.net.
Jonathan L SesslerDepartment of Chemistry, The University of Texas at Austin Austin Texas 78712-1224 USA sessler@cm.utexas.edu.ORCID https://orcid.org/0000-0002-9576-1325
Jiyou HanDepartment of Biological Sciences, Hyupsung University Hwasung-si 18330 Korea hs0101j@gmail.com hanjiyou12@hanmail.net.ORCID https://orcid.org/0000-0001-5749-3086
Jong Seung KimDepartment of Chemistry, Korea University Seoul 02841 Korea jongskim@korea.ac.kr.ORCID https://orcid.org/0000-0003-3477-1172
Hyupsung University · KRKorea University · KRThe University of Texas at Austin · US

Funding

Biomedical Applications of Expanded Porphyrins: Development of Gold-Texaphyrin ConjugatesR01CA068682 · NCI · UNIVERSITY OF TEXAS AUSTIN · PI Esther Y. Maier, Emily L Que · 1995 to 2026
$7.4M
NCI NIH HHS R01 CA068682
6 · The paper itself

Abstract

Chemoresistance originating from cancer stem cells (CSCs) is a major cause of cancer treatment failure and highlights the need to develop CSC-targeting therapies. Although enormous progress in both photodynamic therapy (PDT) and chemodynamic therapy (CDT) has been made in recent decades, the efficacy of these modalities against CSC remains limited. Here, we report a new generation photosensitizer, CA9-BPS-Cu(ii), a system that combines three subunits within a single molecule, namely a copper catalyst for CDT, a boron dipyrromethene photosensitizer for PDT, and acetazolamide for CSC targeting

Identifiers

PMID36819853
PMCPMC9930985
OpenAlexW4320006270

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.