Evidence map›Paper›PMID 36819701›Full record

ArticleFrontiers in nutrition2023

The relationship between fermentable carbohydrates and post-prandial bowel symptoms in patients with functional bowel disorders.

Alice MacIntosh, Phoebe E Heenan, Morag Wright-McNaughton, Chris Frampton, Paula Skidmore, Catherine L Wall, Jane Muir, Nicholas Joseph Talley, Nicole Clemence Roy, Richard B Gearry

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07000227 (Mechanism of FODMAP Restriction on Gut Microbiota and Gut Barrier Function in Functional Gastrointestinal Disorder Patients), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07000227 narecruitingnot on this mapstarted 2025, after this paper: background citation

Mechanism of FODMAP Restriction on Gut Microbiota and Gut Barrier Function in Functional Gastrointestinal Disorder Patients : A Randomised Controlled Trial

TypeinterventionalSponsorUniversiti Kebangsaan Malaysia Medical CentreRan2025 to 2026Enrolled60ConditionsFunctional Gastrointestinal Disorders (FGIDs), Irritable Bowel Syndrome (IBS), Functional DyspepsiaArmsLow FODMAP diet, Gentle FODMAP diet, Traditional Dietary Advice
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Alice MacIntoshDepartment of Human Nutrition, University of Otago, Dunedin, New Zealand.
Phoebe E HeenanDepartment of Medicine, University of Otago, Christchurch, New Zealand.
Morag Wright-McNaughtonDepartment of Human Nutrition, University of Otago, Dunedin, New Zealand.
Chris FramptonDepartment of Medicine, University of Otago, Christchurch, New Zealand.
Paula SkidmoreDepartment of Human Nutrition, University of Otago, Dunedin, New Zealand.
Catherine L WallDepartment of Medicine, University of Otago, Christchurch, New Zealand.
Jane MuirDepartment of Gastroenterology, Monash University, Melbourne, VIC, Australia.
Nicholas Joseph TalleySchool of Medicine, University of Newcastle, Newcastle, NSW, Australia.
Nicole Clemence RoyDepartment of Human Nutrition, University of Otago, Dunedin, New Zealand.
Richard B GearryDepartment of Medicine, University of Otago, Christchurch, New Zealand.
University of Otago · NZUniversity of Auckland · NZMonash University · AURiddet Institute · NZUniversity of Newcastle Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: A low fermentable oligosaccharide, disaccharide, monosaccharide, and polyols (FODMAP) diet alleviates symptoms of irritable bowel syndrome (IBS). We aimed to investigate the relationship between habitual FODMAP intake and post-prandial bowel symptoms in adults with IBS, functional diarrhoea (FD), or constipation (FD) (functional bowel disorders), and in healthy adults (controls). Methods: 292 participants (173 with functional bowel disorders and 119 controls) completed a food and symptom times diary. Estimated meal portion sizes were entered into the Monash FODMAP Calculator to analyse FODMAP content. Wilcoxon and ANOVA tests were used to investigate the relationship between FODMAP intake and post-prandial bowel symptoms. Results: IBS participants experienced more post-prandial bowel symptoms compared to participants with other functional bowel disorders or controls. Meals associated with abdominal pain contained on average increased excess fructose (0.31 g vs. 0.18 g, Conclusion: These findings support the role of FODMAP in post-prandial bowel symptom onset, however, the amount and type of FODMAP triggering symptoms vary between individuals. Future research should investigate the relationship between the effect of individual FODMAP consumption on post-prandial bowel symptoms for each subtype, the interaction of FODMAP with differing functional bowel disorders and whether longitudinally symptoms and dietary intake are stable.

Indexed as

dietfiberFODMAPfunctional bowel disordergastrointestinal symptomirritable bowel syndromepost-prandial bowel symptoms

Identifiers

PMID36819701
PMCPMC9932028
OpenAlexW4319035198

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.