Evidence map›Paper›PMID 36819516›Full record

ArticleAnnals of translational medicine2023

Ozone reduces ischemic damage after a stroke by regulating the autophagy of astrocytes.

Ni Huang, Duangui Gao, Shi Zhou, Zhi Huang

Open access · diamondAbstract read
In one paragraph

Article in Annals of translational medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Ni HuangSuzhou Medical College of Soochow University, Suzhou, China.
Duangui GaoInstitute of Image, Guizhou Medical University, Guiyang, China.
Shi ZhouInstitute of Image, Guizhou Medical University, Guiyang, China.
Zhi HuangDepartment of Interventional Radiology, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Guiyang Medical University · CNAffiliated Hospital of Guizhou Medical University · CNSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Stroke is a common and damaging disease of brain tissue, and has high morbidity, disability, and mortality rates. Ozone (O Methods: First, oxygen-glucose deprivation/reoxygenation (OGD/R)-induced human glioblastoma cell (A172) and middle cerebral artery occlusion (MCAO) rat models were established. Second, the levels of the associated ribonucleic acids and proteins were analyzed using reverse-transcription real-time-quantitative polymerase chain reaction, Western Blot, or immunofluorescence assays. Third, the concentration of glutamate and lactate dehydrogenase (LDH) were assessed using enzyme-linked immunoassays. Results: The results showed that glial fibrillary acidic protein was upregulated in the OGD/R A172 cells. O Conclusions: Thus, O

Indexed as

ischemic damageOzonepropofolstroke

Identifiers

PMID36819516
PMCPMC9929848
OpenAlexW4316668639

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.