Evidence map›Paper›PMID 36819466›Full record

ArticleJournal of contemporary brachytherapy2022

Radiation exposure to the kidney with interstitial iridium-192 high-dose-rate brachytherapy: Extent and rare morphologic changes of radiation nephropathy.

Christine March, Maximilian Thormann, Peter Hass, Max Seidensticker, Christian Gross, Jazan Omari, Maciej Pech, Robert Damm

Open access · goldAbstract read
In one paragraph

Article in Journal of contemporary brachytherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 70% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Christine MarchDepartment of Radiology and Nuclear Medicine, Otto-von-Guericke-University Magdeburg, Germany.
Maximilian ThormannDepartment of Radiology and Nuclear Medicine, Otto-von-Guericke-University Magdeburg, Germany.
Peter HassDepartment of Radiotherapy and Radiooncology, Helios-Klinikum Erfurt GmbH, Germany.
Max SeidenstickerDepartment of Radiology, Ludwig-Maximilians-University Munich, Germany.
Christian GrossDepartment of Nephrology, Hypertensive Diseases, Diabetology and Endocrinology, Otto-von-Guericke-University Magdeburg, Germany.
Jazan OmariDepartment of Radiology and Nuclear Medicine, Otto-von-Guericke-University Magdeburg, Germany.
Maciej PechDepartment of Radiology and Nuclear Medicine, Otto-von-Guericke-University Magdeburg, Germany.
Robert DammDepartment of Radiology and Nuclear Medicine, Otto-von-Guericke-University Magdeburg, Germany.
Otto-von-Guericke University Magdeburg · DEHelios Klinikum Erfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: We sought to investigate functional parameters and morphologic changes of the renal parenchyma after treatment with image-guided brachytherapy using single-fraction irradiation (high-dose-rate brachytherapy - HDR-BT) of primary kidney lesions, and primary and secondary lesions of the liver, lymph node, and adrenal gland close to renal structures. Material and methods: Patients ineligible for surgery were included. We prospectively investigated renal function loss within one year Results: In total, 35 patients were included (21 males, 14 females). Eight patients were treated for extra-renal malignancies. The mean V Conclusions: CT-guided HDR-BT is a viable treatment modality for local ablative treatment of renal and adjacent masses, with no significant reduction of the KDOQI stage as a predictor for complications of chronic kidney disease. However, larger cohorts need to be analyzed to identify vulnerable patients, as in rare cases, plain dosimetry seems insufficient to predict renal function loss after HDR-BT.

Indexed as

brachytherapyradiation-induced nephropathyrenal dysfunctionsingle-fraction irradiation

Identifiers

PMID36819466
PMCPMC9924155
OpenAlexW4316652104

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.