Evidence map›Paper›PMID 36819269›Full record

ArticleQuantitative imaging in medicine and surgery2023

Deep learning attention-guided radiomics for COVID-19 chest radiograph classification.

Dongrong Yang, Ge Ren, Ruiyan Ni, Yu-Hua Huang, Ngo Fung Daniel Lam, Hongfei Sun, Shiu Bun Nelson Wan, Man Fung Esther Wong, King Kwong Chan, Hoi Ching Hailey Tsang and 8 more

Open access · diamondAbstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

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  3. [Detection of neurofibroma combining radiomics and ensemble learning].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 2 countries.

Dongrong YangDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China.
Ge RenDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China.
Ruiyan NiDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China.
Yu-Hua HuangDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China.
Ngo Fung Daniel LamDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China.
Hongfei SunDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China.
Shiu Bun Nelson WanDepartment of Radiology, Pamela Youde Nethersole Eastern Hospital, Hong Kong, China.
Man Fung Esther WongDepartment of Radiology, Pamela Youde Nethersole Eastern Hospital, Hong Kong, China.
King Kwong ChanDepartment of Radiology and Imaging, Queen Elizabeth Hospital, Hong Kong, China.
Hoi Ching Hailey TsangDepartment of Radiology and Imaging, Queen Elizabeth Hospital, Hong Kong, China.
Lu XuDepartment of Radiology and Imaging, Queen Elizabeth Hospital, Hong Kong, China.
Tak Chiu WuDepartment of Radiology and Imaging, Queen Elizabeth Hospital, Hong Kong, China.
Feng-Ming Spring KongDepartment of Clinical Oncology, The University of Hong Kong, Hong Kong, China.
Yì Xiáng J WángDeparment of Imaging and Interventional Radiology, The Chinese University of Hong Kong, Hong Kong, China.
Jing QinSchool of Nursing, The Hong Kong Polytechnic University, Hong Kong, China.
Lawrence Wing Chi ChanDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China.
Michael YingDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China.
Jing CaiDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China.
Hong Kong Polytechnic University · HKQueen Elizabeth Hospital · CNPamela Youde Nethersole Eastern Hospital · CNChinese University of Hong Kong · CNUniversity of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Accurate assessment of coronavirus disease 2019 (COVID-19) lung involvement through chest radiograph plays an important role in effective management of the infection. This study aims to develop a two-step feature merging method to integrate image features from deep learning and radiomics to differentiate COVID-19, non-COVID-19 pneumonia and normal chest radiographs (CXR). Methods: In this study, a deformable convolutional neural network (deformable CNN) was developed and used as a feature extractor to obtain 1,024-dimensional deep learning latent representation (DLR) features. Then 1,069-dimensional radiomics features were extracted from the region of interest (ROI) guided by deformable CNN's attention. The two feature sets were concatenated to generate a merged feature set for classification. For comparative experiments, the same process has been applied to the DLR-only feature set for verifying the effectiveness of feature concatenation. Results: Using the merged feature set resulted in an overall average accuracy of 91.0% for three-class classification, representing a statistically significant improvement of 0.6% compared to the DLR-only classification. The recall and precision of classification into the COVID-19 class were 0.926 and 0.976, respectively. The feature merging method was shown to significantly improve the classification performance as compared to using only deep learning features, regardless of choice of classifier (P value <0.0001). Three classes' F1-score were 0.892, 0.890, and 0.950 correspondingly (i.e., normal, non-COVID-19 pneumonia, COVID-19). Conclusions: A two-step COVID-19 classification framework integrating information from both DLR and radiomics features (guided by deep learning attention mechanism) has been developed. The proposed feature merging method has been shown to improve the performance of chest radiograph classification as compared to the case of using only deep learning features.

Indexed as

chest radiographclassificationCoronavirus disease 2019 (COVID-19)deep learningradiomics

Identifiers

PMID36819269
PMCPMC9929417
OpenAlexW4312767071

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.