ArticleQuantitative imaging in medicine and surgery2023
Phantom-based quantification of the spectral accuracy in dual-layer spectral CT for pediatric imaging at 100 kVp.
Article in Quantitative imaging in medicine and surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 9 citations in OpenAlex.
- The diagnostic efficacy of venous-phase spectral CT combined with Node-RADS for differentiating enlarged lymph nodes in common solid tumors: a preliminary exploratory study.Frontiers in oncology · 2026Article
- Phantom-based quantification of the spectral accuracy of lower extremity vascular imaging using a second-generation dual-layer spectral CT at 100 kVp and 120kVp.BMC medical imaging · 2025Article
- Impact of acquisition and reconstruction parameters on quantitative accuracy in dual-layer spectral CT: A phantom study.Journal of applied clinical medical physics · 2025Article
- Efficient spectral data reduction for accurate iodine quantification in multi-energy CT.Scientific reports · 2025Article
- A prediction model based on dual-layer spectral detector computed tomography for distinguishing nonluminal from luminal invasive breast cancer.Quantitative imaging in medicine and surgery · 2024Article
- Impact of scatter radiation on spectral quantification performance of first- and second-generation dual-layer spectral computed tomography.Journal of applied clinical medical physics · 2024Article
- Spectral performance evaluation of a second-generation spectral detector CT.Journal of applied clinical medical physics · 2024Article
- Fat quantification in dual-layer detector spectral CT: How to handle iron overload, varying tube voltage and radiation dose Indices.PloS one · 2024Article
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Background: To determine the spectral accuracy in detector-based dual-energy CT (DECT) at 100 kVp and wide (8 cm) collimation width for dose levels and object sizes relevant to pediatric imaging. Methods: A spectral CT phantom containing tissue-equivalent materials and iodine inserts of varying concentrations was scanned on the latest generation detector-based DECT system. Two 3D-printed extension rings were used to mimic varying pediatric patient sizes. Scans were performed at 100 and 120 kVp, 4 and 8 cm collimation widths, and progressively reduced radiation dose levels, down to 0.9 mGy CTDI Results: DECT scans at 100 kVp provided highly accurate spectral results; however, a size dependence was observed for iodine quantification. For the medium phantom configuration (15 cm diameter), measurement errors in iodine density, effective atomic number, and electron density (ED) were below 0.3 mg/mL, 0.2 and 1.8 %ED Conclusions: Detector-based DECT at 100 kVp can provide on-demand or retrospective spectral information with high accuracy even at extremely low doses, thereby making it an attractive solution for pediatric imaging.
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