Evidence map›Paper›PMID 36819145›Full record

ArticleEJHaem2023

Phase I study of novel SYK inhibitor TAK-659 (mivavotinib) in combination with R-CHOP for front-line treatment of high-risk diffuse large B-cell lymphoma.

Reem Karmali, Frederique St-Pierre, Shuo Ma, Kelly D Foster, Jason Kaplan, Xinlei Mi, Barbara Pro, Jane N Winter, Leo I Gordon

Open access · diamondAbstract read
In one paragraph

Article in EJHaem, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Reem KarmaliRobert H. Lurie Comprehensive Cancer Center, Division of Hematology/Oncology, Feinberg School of Medicine Northwestern University Chicago Illinois USA.ORCID https://orcid.org/0000-0003-0984-4376
Frederique St-PierreRobert H. Lurie Comprehensive Cancer Center, Division of Hematology/Oncology, Feinberg School of Medicine Northwestern University Chicago Illinois USA.
Shuo MaRobert H. Lurie Comprehensive Cancer Center, Division of Hematology/Oncology, Feinberg School of Medicine Northwestern University Chicago Illinois USA.
Kelly D FosterNorthwestern Medicine Lake Forest Hospital Lake Forest Illinois USA.
Jason KaplanRobert H. Lurie Comprehensive Cancer Center, Division of Hematology/Oncology, Feinberg School of Medicine Northwestern University Chicago Illinois USA.
Xinlei MiDepartment of Preventative Medicine - Biostatistics, Feinberg School of Medicine Northwestern University Chicago Illinois USA.
Barbara ProRobert H. Lurie Comprehensive Cancer Center, Division of Hematology/Oncology, Feinberg School of Medicine Northwestern University Chicago Illinois USA.
Jane N WinterRobert H. Lurie Comprehensive Cancer Center, Division of Hematology/Oncology, Feinberg School of Medicine Northwestern University Chicago Illinois USA.
Leo I GordonRobert H. Lurie Comprehensive Cancer Center, Division of Hematology/Oncology, Feinberg School of Medicine Northwestern University Chicago Illinois USA.
Northwestern University · USNorthwestern Medicine Lake Forest Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

aggressive non‐Hodgkin's lymphomadiffuse large B‐cell lymphomamivavotinibSYK inhibitorTAK‐659

Identifiers

PMID36819145
PMCPMC9928783
OpenAlexW4310679729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.