ArticleFrontiers in plant science2023
Global transcriptome and gene co-expression network analyses reveal regulatory and non-additive effects of drought and heat stress in grapevine.
Article in Frontiers in plant science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- Dynamic and non-additive gene regulation shapes maize responses to simultaneous salt and cold stress.Functional & integrative genomics · 2026Article
- Genomics, Multi-Omics, and Emerging Artificial Intelligence for Combined Drought-Heat Stress Resilience in Plants: A Structured Narrative Review.Plants (Basel, Switzerland) · 2026Review
- Molecular Mechanisms in Responses to Combined Stresses in Strawberry.Current issues in molecular biology · 2026Review
- Molecular Mechanisms of Plant Stress Tolerance: From Stress Perception to Phytohormonal Crosstalk and Transcriptional Regulation.Current issues in molecular biology · 2026Review
- Article
- Combined omics data reveal multilevel response to water deficit in grapevine disease-resistant varieties.Frontiers in plant science · 2026Article
- Emerging Mechanisms of Plant Responses to Abiotic Stress.Plants (Basel, Switzerland) · 2025Review
- Responding to Stress: Diversity and Resilience of Grapevine in a Changing Climate Under the Perspective of Omics Research.International journal of molecular sciences · 2025Review
- Enhancing Abiotic Stress Resilience in Mediterranean Woody Perennial Fruit Crops: Genetic, Epigenetic, and Microbial Molecular Perspectives in the Face of Climate Change.International journal of molecular sciences · 2025Review
- Transcriptomic Analyses Reveal ThatInternational journal of molecular sciences · 2024Article
- Canopy Architecture and Sun Exposure Influence Berry Cluster-Water Relations in the Grapevine Variety Muscat of Alexandria.Plants (Basel, Switzerland) · 2024Article
- Emerging Roles of Epigenetics in Grapevine and Winegrowing.Plants (Basel, Switzerland) · 2024Review
- Advancing tree genomics to future proof next generation orchard production.Frontiers in plant science · 2023Review
- Polyploidization and genomic selection integration for grapevine breeding: a perspective.Frontiers in plant science · 2023Review
- Investigating the impact of pedoclimatic conditions on the oenological performance of two red cultivars grown throughout southern Italy.Frontiers in plant science · 2023Article
- When drought meets heat - a plant omics perspective.Frontiers in plant science · 2023Review
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite frequent co-occurrence of drought and heat stress, the molecular mechanisms governing plant responses to these stresses in combination have not often been studied. This is particularly evident in non-model, perennial plants. We conducted large scale physiological and transcriptome analyses to identify genes and pathways associated with grapevine response to drought and/or heat stress during stress progression and recovery. We identified gene clusters with expression correlated to leaf temperature and water stress and five hub genes for the combined stress co-expression network. Several differentially expressed genes were common to the individual and combined stresses, but the majority were unique to the individual or combined stress treatments. These included heat-shock proteins, mitogen-activated kinases, sugar metabolizing enzymes, and transcription factors, while phenylpropanoid biosynthesis and histone modifying genes were unique to the combined stress treatment. Following physiological recovery, differentially expressed genes were found only in plants under heat stress, both alone and combined with drought. Taken collectively, our results suggest that the effect of the combined stress on physiology and gene expression is more severe than that of individual stresses, but not simply additive, and that epigenetic chromatin modifications may play an important role in grapevine responses to combined drought and heat stress.
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Registered trials
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